Does intravenous ibuprofen have an effect on pain control and drug use after upper limb orthopedic surgery? A double-blind randomized clinical trial Study

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MALEKSHOAR MEHRDAD; VATANKHAH MAJID

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Journal: Pars Journal of Medical Sciences Year:2021 | Volume:19 | Issue:2 Page(s): 14-22

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Information Journal Paper

Title

Does intravenous ibuprofen have an effect on pain control and drug use after upper limb orthopedic surgery? A double-blind randomized clinical trial Study

Author(s)

MALEKSHOAR MEHRDAD | VATANKHAH MAJID | Issue Writer Certificate

Keywords

Intravenous ibuprofen

Pain

Orthopedics

Upper limb

Drug use

Abstract

Introduction: Pain after surgery is an unpleasant experience. This process causes physiological disorders in all systems of the body. Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs to control postoperative Pain. Therefore, this study was performed to evaluate the effect of ibuprofen intravenous on Pain control and opioid use after Upper limb orthopedic surgery. Materials and Methods: In this randomized double-blind clinical trial study, 60 patients with anesthesia class I and II underwent Upper limb orthopedic surgery. Patients were randomly divided into intravenous and control ibuprofen. Systolic and diastolic blood pressure, mean arterial pressure and heart rate before surgery, 1, 10 and 20 minutes after surgery were recorded. Pain was measured before, 6, 12 and 24 hours after surgery. Postoperative Drug use was recorded in both groups. Data analysis was performed using SPSS software version 21 and using descriptive and inferential statistical tests. Results: Ibuprofen and control groups were similar in terms of gender, age, BMI and ASA. The results of Chisquare test showed that in recovery and 6 and 12 hours after surgery, Pain in patients in the ibuprofen group was significantly less than the control group (P<0. 05). Also, the intragroup Pain trend was significant in ibuprofen and control groups (P<0. 05). Mean Pain in ibuprofen group decreased more than control (P<0. 001). Comparison of opioid use was significant in ibuprofen group (6. 7% of Apotel and 6. 7% of pethidine) and control group (30% of patients with pethidine) (P-value = 0. 030). Conclusion: The results of the present study showed that Intravenous ibuprofen is better in controlling Pain intensity and Drug use than the control group. Ibuprofen seems to be very effective in controlling Pain and postoperative Drug use in orthopedic surgeries.

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APA: Copy

MALEKSHOAR, MEHRDAD, & VATANKHAH, MAJID. (2021). Does intravenous ibuprofen have an effect on pain control and drug use after upper limb orthopedic surgery? A double-blind randomized clinical trial Study. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 19(2 ), 14-22. SID. https://sid.ir/paper/954050/en

Vancouver: Copy

MALEKSHOAR MEHRDAD, VATANKHAH MAJID. Does intravenous ibuprofen have an effect on pain control and drug use after upper limb orthopedic surgery? A double-blind randomized clinical trial Study. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2021;19(2 ):14-22. Available from: https://sid.ir/paper/954050/en

IEEE: Copy

MEHRDAD MALEKSHOAR, and MAJID VATANKHAH, “Does intravenous ibuprofen have an effect on pain control and drug use after upper limb orthopedic surgery? A double-blind randomized clinical trial Study,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 19, no. 2 , pp. 14–22, 2021, [Online]. Available: https://sid.ir/paper/954050/en

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