The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats

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SALEHI ANAHITA; FARZANEGI PARVIN; Abbaszadeh Hajar

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Journal: JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:7 | Issue:1 (22) Page(s): 112-121

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Title

The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats

Author(s)

SALEHI ANAHITA | FARZANEGI PARVIN | Abbaszadeh Hajar | Issue Writer Certificate

Keywords

Continuous Exercise

Interval Exercise

Diabetes

apoptosis

resveratrol

Abstract

Introduction Diabetes is the leading cause of mortality. Therefore, the purpose of this study was to investigate the effect of interval and continuous training with resveratrol on the apoptosis markers (Bax and Bcl2) of heart tissue in streptozotocininduced diabetic rats. Materials and Methods In this experimental study, wistar male rats were divided into 8 groups (control-healthy (n=7), control Diabetes (n=7), Diabetes-saline, Diabetessupplement, Diabetes-continuous training, Diabetes-interval training, Diabetescontinuous training-supplement, and Diabetes-interval training-supplement). The main continuous training program included 8 weeks, five sessions per week, 15-20 m / min and 60 minutes and interval training included 8 weeks, 3 sessions per week. resveratrol at a dose of 20 mg per kg body weight was injected to the supplement groups. The rats have been sacrificed 48 hours after the last trainingand supplements session> Then, the heart tissue is removed and used to measure the desired variables. Results The heart levels of BAX and Bcl2 showed a significant difference between the groups (P = 0. 046). The data showed a significant difference between the control Diabetes with the Diabetes-supplement, Diabetes-continuous training, Diabetes-interval training, Diabetes-continuous training-supplement, Diabetesinterval training-supplement (P <0. 001). Conclusion The results of this study showed that exercise trainings increase the Bcl2 and decrease Bax levels. This improvement was higher when resveratrol was used.

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APA: Copy

SALEHI, ANAHITA, FARZANEGI, PARVIN, & Abbaszadeh, Hajar. (2019). The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, 7(1 (22) ), 112-121. SID. https://sid.ir/paper/955909/en

Vancouver: Copy

SALEHI ANAHITA, FARZANEGI PARVIN, Abbaszadeh Hajar. The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats. JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;7(1 (22) ):112-121. Available from: https://sid.ir/paper/955909/en

IEEE: Copy

ANAHITA SALEHI, PARVIN FARZANEGI, and Hajar Abbaszadeh, “The effect of interval and continuous training with resveratrol on some of the oxidative stress markers of heart tissue in streptozotocin-induced diabetic rats,” JOURNAL OF NEYSHABUR UNIVERSITY OF MEDICAL SCIENCES, vol. 7, no. 1 (22) , pp. 112–121, 2019, [Online]. Available: https://sid.ir/paper/955909/en

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