Weight loss in male rats is caused by the hydroalcoholic extract of ephedra due to an increase in the serum concentration of hormone adiponectin

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Sakeh Shiva; ATASHPOUR SHEKOUFEH; RAHIMIPOUR MARZIEH; Abedi Hassanali; Sarvarzadeh Mahsasadat; KARGAR JAHROMI HOSSEIN

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Journal: Pars Journal of Medical Sciences Year:2021 | Volume:19 | Issue:2 Page(s): 33-37

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Title

Weight loss in male rats is caused by the hydroalcoholic extract of ephedra due to an increase in the serum concentration of hormone adiponectin

Author(s)

Keywords

Ephedra

Adiponectin

Body Weight

Rat

Abstract

Introduction: Drugs and supplements containing Ephedra extract have been always noticed by researchers as a plant known for weight loss and control. The aim of the present study was to evaluate the effect of Ephedra hydroalcoholic extract on serum Adiponectin level and Body Weight in male Rats. Materials and Methods: In this experimental study, 40 adult male Wistar Rats were selected and randomly divided into 5 equal groups including: control (without receiving any substances), control (receiving 1 mL of distilled water), experimental group 1 (recipient of 250 mg/kg Ephedra hydroalcoholic extract), experimental group 2 (recipient of 500 mg/kg Ephedra hydroalcoholic extract) and experimental group 3 (recipient of 1000 mg/kg Ephedra hydroalcoholic extract). In the experimental groups, the extract was administered by gavage for 28 days. On the 29th day, blood samples were taken from the Rats to check the serum levels of the hormone Adiponectin. Body Weight of Rats was also measured daily during the experimental period. Data were analyzed by one-way ANOVA using SPSS software and Duncan test. Results: Doses of 500 and 1000 mg/kg of Ephedra hydroalcoholic extract caused a significant increase in serum levels of Adiponectin and also a decrease in Body Weight compared to the control group (P≤ 0. 05). Conclusion: Ephedra hydroalcoholic extract reduces Body Weight by increasing serum levels of the hormone Adiponectin.

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APA: Copy

Sakeh, Shiva, ATASHPOUR, SHEKOUFEH, RAHIMIPOUR, MARZIEH, Abedi, Hassanali, Sarvarzadeh, Mahsasadat, & KARGAR JAHROMI, HOSSEIN. (2021). Weight loss in male rats is caused by the hydroalcoholic extract of ephedra due to an increase in the serum concentration of hormone adiponectin. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 19(2 ), 33-37. SID. https://sid.ir/paper/955913/en

Vancouver: Copy

Sakeh Shiva, ATASHPOUR SHEKOUFEH, RAHIMIPOUR MARZIEH, Abedi Hassanali, Sarvarzadeh Mahsasadat, KARGAR JAHROMI HOSSEIN. Weight loss in male rats is caused by the hydroalcoholic extract of ephedra due to an increase in the serum concentration of hormone adiponectin. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2021;19(2 ):33-37. Available from: https://sid.ir/paper/955913/en

IEEE: Copy

Shiva Sakeh, SHEKOUFEH ATASHPOUR, MARZIEH RAHIMIPOUR, Hassanali Abedi, Mahsasadat Sarvarzadeh, and HOSSEIN KARGAR JAHROMI, “Weight loss in male rats is caused by the hydroalcoholic extract of ephedra due to an increase in the serum concentration of hormone adiponectin,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 19, no. 2 , pp. 33–37, 2021, [Online]. Available: https://sid.ir/paper/955913/en

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