EFFECT OF ATORVASTATIN ON BLOOD AND GASOMETRICAL PARAMETERS IN PATIENTS WITH COPD: A DOUBLE-BLIND CONTROLLED CLINICAL TRIAL (SHORT COMMUNICATION)

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MORTAZAVI MOGHADAM SAYYED GHOLAMREZA; ARIAN ANAHITA; KAZEMI TOBA; Hajihosseini Morteza; ZARDAST MAHMOOD

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Journal: Journal of Birjand University of Medical Sciences Year:2017 | Volume:23 | Issue:4 Page(s): 334-341

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Title

EFFECT OF ATORVASTATIN ON BLOOD AND GASOMETRICAL PARAMETERS IN PATIENTS WITH COPD: A DOUBLE-BLIND CONTROLLED CLINICAL TRIAL (SHORT COMMUNICATION)

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Keywords

ATORVASTATINQ2

COPDQ1

HEMOGLOBINQ3

WBCQ3

O2 SATURATIONQ3

Abstract

Chronic obstructive pulmonary disease (COPD) is a syndrome with progressive and irreversible airflow limitation. The aim of this study was to evaluate the effect of ATORVASTATINs on blood parameters including blood gasses in patients with COPD. This randomized double-blind, controlled clinical trial study was conducted on the case and control groups of patients with COPD in Vali-e-asr hospital in Birjand in 2015. In the laboratory, 15 cc of venous blood was taken from each subject. Initial tests included white blood count (WBCs), HEMOGLOBIN (Hb), PH, and Pco2.O2 saturation was observed at rest by means of Pulse Oximeter for the duration of one minute and the highest value was recorded. Out of the 34 patients, 18 cases (52.9%) were treated by ATORVASTATIN and 16 (47.1%). received conventional treatment Mean age of the ATORVASTATIN and control group was 65.8±11.5 and 63.7±7.6 years, respectively. The case group showed a significant decrease in mean count of WBC and HEMOGLOBIN, but increase in O2 SATURATION after intervention. In conclusion, it can be concluded that taking ATORVASTATIN has a significant impact on the reduction of HEMOGLOBIN and increase of oxygen saturation in COPD patients, which requires further studies.

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APA: Copy

MORTAZAVI MOGHADAM, SAYYED GHOLAMREZA, ARIAN, ANAHITA, KAZEMI, TOBA, Hajihosseini, Morteza, & ZARDAST, MAHMOOD. (2017). EFFECT OF ATORVASTATIN ON BLOOD AND GASOMETRICAL PARAMETERS IN PATIENTS WITH COPD: A DOUBLE-BLIND CONTROLLED CLINICAL TRIAL (SHORT COMMUNICATION). JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 23(4), 334-341. SID. https://sid.ir/paper/95602/en

Vancouver: Copy

MORTAZAVI MOGHADAM SAYYED GHOLAMREZA, ARIAN ANAHITA, KAZEMI TOBA, Hajihosseini Morteza, ZARDAST MAHMOOD. EFFECT OF ATORVASTATIN ON BLOOD AND GASOMETRICAL PARAMETERS IN PATIENTS WITH COPD: A DOUBLE-BLIND CONTROLLED CLINICAL TRIAL (SHORT COMMUNICATION). JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2017;23(4):334-341. Available from: https://sid.ir/paper/95602/en

IEEE: Copy

SAYYED GHOLAMREZA MORTAZAVI MOGHADAM, ANAHITA ARIAN, TOBA KAZEMI, Morteza Hajihosseini, and MAHMOOD ZARDAST, “EFFECT OF ATORVASTATIN ON BLOOD AND GASOMETRICAL PARAMETERS IN PATIENTS WITH COPD: A DOUBLE-BLIND CONTROLLED CLINICAL TRIAL (SHORT COMMUNICATION),” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 23, no. 4, pp. 334–341, 2017, [Online]. Available: https://sid.ir/paper/95602/en

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