Effect of Chromium Picolinate Supplementation Combined With Resistance Training on Liver Enzymes Levels and Insulin Resistance in Patients With Type 2 Diabetes

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PARASTESH MOHAMMAD; SAREMI ABBAS; Ebadinejad Meisam

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Paper Information

Journal: Complementary Medicine Journal Year:2019 | Volume:9 | Issue:3 (32) Page(s): 3792-3803

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Information Journal Paper

Title

Effect of Chromium Picolinate Supplementation Combined With Resistance Training on Liver Enzymes Levels and Insulin Resistance in Patients With Type 2 Diabetes

Author(s)

PARASTESH MOHAMMAD | SAREMI ABBAS | Ebadinejad Meisam | Issue Writer Certificate

Keywords

Diabetes

Resistance training

Chromium picolinate supplement

Liver enzymes

Insulin resistance index

Abstract

Objective: The aim of this study was to investigate the effect of supplementation with chromium picolinate combined with Resistance training on the serum level of Liver enzymes and Insulin resistance index (HOMA-IR) in male patients with Type 2 Diabetes (T2D). Methods: In this study, participants were 30 male patients with T2D (Mean± SD weight: 75. 1± 6. 3 kg and BMI= 26. 1± 2. 3 kg/m2). They were divided into three groups (two experimental and one control). In addition to Resistance training for 8 weeks, experimental groups consumed 400-mg chromium picolinate daily and placebo. Serum levels of Liver enzymes, insulin and glucose were measured before and after the training period. Data were analyzed using one-way ACNOVA and Bonferroni correction test (P<0. 05). Results: Both Resistance training combined with Chromium picolinate supplementation (P=0. 04) and Resistance training with placebo (P=0. 11) significantly reduced HOMA-IR compared to the control group. They both also resulted in a significant decrease in Alanine Aminotransferase (ALT) and Aspartate Aminotransferase (AST) enzymes level compared to the diabetic control group (P=0. 01). Resistance training along with Chromium picolinate supplementation (P=0. 01) significantly reduced the waist-hip ratio (P=0. 04) and fat percentage (P=0. 01) compared to controls. Conclusion: training combined with Chromium picolinate supplementation is more effective in improving the Liver enzymes level in T2D patients.

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APA: Copy

PARASTESH, MOHAMMAD, SAREMI, ABBAS, & Ebadinejad, Meisam. (2019). Effect of Chromium Picolinate Supplementation Combined With Resistance Training on Liver Enzymes Levels and Insulin Resistance in Patients With Type 2 Diabetes. COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY, 9(3 (32) ), 3792-3803. SID. https://sid.ir/paper/956204/en

Vancouver: Copy

PARASTESH MOHAMMAD, SAREMI ABBAS, Ebadinejad Meisam. Effect of Chromium Picolinate Supplementation Combined With Resistance Training on Liver Enzymes Levels and Insulin Resistance in Patients With Type 2 Diabetes. COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY[Internet]. 2019;9(3 (32) ):3792-3803. Available from: https://sid.ir/paper/956204/en

IEEE: Copy

MOHAMMAD PARASTESH, ABBAS SAREMI, and Meisam Ebadinejad, “Effect of Chromium Picolinate Supplementation Combined With Resistance Training on Liver Enzymes Levels and Insulin Resistance in Patients With Type 2 Diabetes,” COMPLEMENTARY MEDICINE JOURNAL OF FACULTY OF NURSING & MIDWIFERY, vol. 9, no. 3 (32) , pp. 3792–3803, 2019, [Online]. Available: https://sid.ir/paper/956204/en

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