FACTORS ASSOCIATED WITH CYCLOSPORINE A-INDUCED GINGIVAL ENLARGEMENT IN KIDNEY TRANSPLANT PATIENTS

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KIA SEYED JAVAD; VADIATI SABERI BARDIA; KOCHAKI PASIKHANI AHMAD; NEMATI SOMAYEH

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Journal: Journal of Birjand University of Medical Sciences Year:2015 | Volume:21 | Issue:4 Page(s): 462-468

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Title

FACTORS ASSOCIATED WITH CYCLOSPORINE A-INDUCED GINGIVAL ENLARGEMENT IN KIDNEY TRANSPLANT PATIENTS

Author(s)

KIA SEYED JAVAD | VADIATI SABERI BARDIA | KOCHAKI PASIKHANI AHMAD | NEMATI SOMAYEH | Issue Writer Certificate

Keywords

CYCLOSPORINEQ3

GINGIVAL ENLARGEMENTQ3

KIDNEY TRANSPLANTQ3

Abstract

Background and Aim: CYCLOSPORINE-A (CsA) is commonly prescribed for KIDNEY TRANSPLANT patients to suppress their immune systems, which can lead to GINGIVAL ENLARGEMENT (GE). The present study aimed at determining the prevalence of associated factors with CsA-induced GINGIVAL ENLARGEMENT in KIDNEY TRANSPLANT patients in Rasht during 2012.Materials and Methods: In this cross sectional research, information about KIDNEY TRANSPLANT patients was recorded in respective questionnaires after their examinations. Then, GINGIVAL ENLARGEMENT and gingival index (GI) were divided into 4 degrees at 4 points; and plaque index (PI) was recorded according to Oleary index. Finally, the obtained results were analyzed by means of SPSS Software (V:16), using Chi-square and T-Test.Results: Seventy-five renal transplant patients (31 women and 44 men) with the mean age 43.18 years (age range 18-73years) participated in this study. GINGIVAL ENLARGEMENT was diagnosed in 50% of the patients that had used CYCLOSPORINE. The average dosage of the drug was 179.6 mg. The increased prevalence of GINGIVAL ENLARGEMENT was observed in the maxilla rather than in the mandible and more in the anterior than in the posterior parts of the jaws. GINGIVAL ENLARGEMENT was significantly correlated with GI and PI (P=0.01 and P=0.03, respectively).Conclusion: PI and GI were higher in patients with GINGIVAL ENLARGEMENT than patients without GINGIVAL ENLARGEMENT. Thus, it is suggested that periodontal proper hygiene be done to prevent GINGIVAL ENLARGEMENT.

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APA: Copy

KIA, SEYED JAVAD, VADIATI SABERI, BARDIA, KOCHAKI PASIKHANI, AHMAD, & NEMATI, SOMAYEH. (2015). FACTORS ASSOCIATED WITH CYCLOSPORINE A-INDUCED GINGIVAL ENLARGEMENT IN KIDNEY TRANSPLANT PATIENTS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, 21(4), 462-468. SID. https://sid.ir/paper/95667/en

Vancouver: Copy

KIA SEYED JAVAD, VADIATI SABERI BARDIA, KOCHAKI PASIKHANI AHMAD, NEMATI SOMAYEH. FACTORS ASSOCIATED WITH CYCLOSPORINE A-INDUCED GINGIVAL ENLARGEMENT IN KIDNEY TRANSPLANT PATIENTS. JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;21(4):462-468. Available from: https://sid.ir/paper/95667/en

IEEE: Copy

SEYED JAVAD KIA, BARDIA VADIATI SABERI, AHMAD KOCHAKI PASIKHANI, and SOMAYEH NEMATI, “FACTORS ASSOCIATED WITH CYCLOSPORINE A-INDUCED GINGIVAL ENLARGEMENT IN KIDNEY TRANSPLANT PATIENTS,” JOURNAL OF BIRJAND UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 4, pp. 462–468, 2015, [Online]. Available: https://sid.ir/paper/95667/en

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