The effect of two-month concurrent training and caloric restriction on P65 amount in Peripheral blood mononuclear cells of inactive middle-aged men

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

JAFARI AFSHAR; Etemadian Farid; BARADARAN BEHZAD; MALEKIRAD ALI AKBAR

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Sport and Exercise Physiology Year:2022 | Volume:14 | Issue:2 Page(s): 21-32

Download Full-Text

Persian Verion

View:

130

Download:

Cites:

Information Journal Paper

Title

The effect of two-month concurrent training and caloric restriction on P65 amount in Peripheral blood mononuclear cells of inactive middle-aged men

Author(s)

JAFARI AFSHAR | Etemadian Farid | BARADARAN BEHZAD | MALEKIRAD ALI AKBAR | Issue Writer Certificate

Keywords

Concurrent training

Caloric restriction

P65

CRP

Abstract

Purpose: Recognition of mechanisms involved in inflammatory disorders through the aging process and providing appropriate preventive or modulator strategies to improve quality of life are always important challenges in the field of life sciences. Therefore, the present study was conducted to determine the effect of two-month Concurrent training (RT+HIIT) and Caloric restriction on serum CRP and P65 amount in Peripheral blood mononuclear cells of inactive middle-aged men. Methods: Twenty-four inactive, healthy men participated in three homogeneous groups: Caloric restriction (CR), Concurrent training (T) and Concurrent training with Caloric restriction (CRT) groups. Calorie restriction and energy cost in five days a week was about six kcal• kg-1• day-1. The Concurrent training was included five days per week (two sessions of resistance training with 75 to 80% 1RM and three sessions of high intensity interval training with 80-85% heart rate reserve). Baseline and post-intervention P65 in the total and phosphorylated (p-P65) levels in PBMCs were assessed by ELISA. Serum CRP concentration was also measured using immunoturbidimetric. Results: Weight loss in CRT group was significantly higher than the other two groups (P < 0. 05). However, the changes range in fat percentage, maximal oxygen consumption and one-repetition maximum (1RM) of T and CRT groups were significantly higher than CR group (P < 0. 05). Changes in phosphorylated P65 and p-P65 / total P65 ratio in PBMCs of T and CRT groups were significantlyhigher than CR group (P < 0. 05). Conclusion: Based on the present results, two months of Concurrent training and Caloric restriction can reduce some of inflammatory markers in inactive men. In addition, the effect of Concurrent training with and without calorie restriction on the initiators of inflammatory factors is greater than the calorie restriction intervention alone. Therefore, Concurrent training and Caloric restriction are recommended for prevention and confronting obesity and its inflammatory consequences, especially in middle age.

Cites

No record.

References

No record.

Cite

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops