Effect of intravenous injection of hydrocortisone and lidocaine 2% on pain after Propofol injection: a double-blind randomized clinical trial

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

MELEKSHOAR MEHRDAD; JARINESHIN HASHEM; VATANKHAH MAJID

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Pars Journal of Medical Sciences Year:2019 | Volume:17 | Issue:3 Page(s): 43-49

Download Full-Text

Persian Verion

View:

234

Download:

Cites:

Information Journal Paper

Title

Effect of intravenous injection of hydrocortisone and lidocaine 2% on pain after Propofol injection: a double-blind randomized clinical trial

Author(s)

MELEKSHOAR MEHRDAD | JARINESHIN HASHEM | VATANKHAH MAJID | Issue Writer Certificate

Keywords

Lidocaine

Hydrocortisone

Pain intensity

Propofol

Abstract

Introduction: Propofol is an intravenous anesthetic drug that has been widely used in outpatient and short-term surgery due to its rapid recovery. However, pain during Propofol injection can cause discomfort in 28 to 91% of patients. Various sources have argued that the effects of Hydrocortisone and Lidocaine on pain during Propofol injection are contradictory. The present study was investigated the comparison of effect of Hydrocortisone and Lidocaine on pain during Propofol injection. Materials and Methods: In a randomized double-blind clinical trial, 150 patients, aged 15-65 years with ASA I and II physical grade who were candidates for elective surgery under general anesthesia at Shahid Mohammadi Hospital in Bandar Abbas in 2019 were enrolled. They were, randomly divided into 3 groups of 50 subjects'. Group a received Lidocaine 2%, 1 mg / kg; group B received 25 mg Hydrocortisone; and group C received 5 ml saline. The severity and incidence of pain after Propofol injection were evaluated. Data were analyzed by SPSS software, version 19 and analyzed by independent t-test and chi-square or fisher exact test. P-values less than 0. 05 were considered as significant. Results: There was a significant difference in incidence of pain during Propofol injection between the three groups (Lidocaine and Hydrocortisone, Lidocaine and Hydrocortisone with normal saline) (p<0. 001). There was also a significant difference in pain severity between the Lidocaine and Hydrocortisone with normal saline groups, while there was no significant difference between the Lidocaine and Hydrocortisone groups (p= 0. 615). The effect of Hydrocortisone and Lidocaine on pain was not significant. According to sex, age and weight Conclusion: Hydrocortisone and Lidocaine reduce pain during Propofol injection and the effect of Lidocaine was more than Hydrocortisone. However, using of these medications may be able to reduce the pain resulted during Propofol injection.

Cites

No record.

References

No record.

Cite

APA: Copy

MELEKSHOAR, MEHRDAD, JARINESHIN, HASHEM, & VATANKHAH, MAJID. (2019). Effect of intravenous injection of hydrocortisone and lidocaine 2% on pain after Propofol injection: a double-blind randomized clinical trial. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), 17(3 ), 43-49. SID. https://sid.ir/paper/958599/en

Vancouver: Copy

MELEKSHOAR MEHRDAD, JARINESHIN HASHEM, VATANKHAH MAJID. Effect of intravenous injection of hydrocortisone and lidocaine 2% on pain after Propofol injection: a double-blind randomized clinical trial. PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL)[Internet]. 2019;17(3 ):43-49. Available from: https://sid.ir/paper/958599/en

IEEE: Copy

MEHRDAD MELEKSHOAR, HASHEM JARINESHIN, and MAJID VATANKHAH, “Effect of intravenous injection of hydrocortisone and lidocaine 2% on pain after Propofol injection: a double-blind randomized clinical trial,” PARS JOURNAL OF MEDICAL SCIENCES (JAHROM MEDICAL JOURNAL), vol. 17, no. 3 , pp. 43–49, 2019, [Online]. Available: https://sid.ir/paper/958599/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops