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Information Journal Paper

Title

The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient with Cardiac Angina

Pages

  172-179

Abstract

 Background: In a person with significant coronary artery disease (CAD), exercise stress can cause reversible Myocardial ischemia, which is detectable by single photon emission computed tomography-myocardial perfusion imaging (SPECT-MPI). The aim of present study was to investigate the relationship between post-exercise highsensitive cardiac Troponin I (hs-cTnI) serum levels and result of SPECT-MPI as a gold standard. Methods: In this cross-sectional study, 82 patients with no previous history of CAD or any organic disease were evaluated. hs-cTnI serum levels were monitored 75 minutes after the peaked of exercise (achievement to at least 85% of maximum heart rate), and compared with reversible Myocardial ischemia. After 3 months, patients’ prognosis and continued chest pain were evaluated. Findings: The mean age of the patients was 59. 4 ± 11. 1, and 60 patients (73%) were women. In 29 patients, reversible Myocardial ischemia was detected. There was a significant correlation between hs-cTnI serum level and reversible Myocardial ischemia (P = 0. 005); but no significant relationship was seen with infarcted myocardial tissue (P = 0. 063). Based on SPECT-MPI, the hs-cTnI serum amount of 1. 6 ng/dl, as likely as hs-cTnI cut-off level, represented the specificity of 70%, sensitivity of 69%, positive predictive value of 55%, and negative predictive value of 80%. There was no significant relationship between hs-cTnI level and prognosis or chest pain after 3 months. Conclusion: The serum level of hs-cTnI after exercise was higher in the group with reversible Myocardial ischemia.

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    APA: Copy

    SADEGHI, MASOUMEH, MOSLEHI, MASOUD, Teimouri Jervekani, Zahra, & SHAHRAKI, HAMED. (2020). The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient with Cardiac Angina. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 38(568 ), 172-179. SID. https://sid.ir/paper/962388/en

    Vancouver: Copy

    SADEGHI MASOUMEH, MOSLEHI MASOUD, Teimouri Jervekani Zahra, SHAHRAKI HAMED. The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient with Cardiac Angina. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2020;38(568 ):172-179. Available from: https://sid.ir/paper/962388/en

    IEEE: Copy

    MASOUMEH SADEGHI, MASOUD MOSLEHI, Zahra Teimouri Jervekani, and HAMED SHAHRAKI, “The Validity of High-Sensitive Cardiac Troponin I Serum Level in Comparison to Myocardial Perfusion Imaging in Patient with Cardiac Angina,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 38, no. 568 , pp. 172–179, 2020, [Online]. Available: https://sid.ir/paper/962388/en

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