مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Verion
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

333
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Epigenetic Modifications of Host Genes Induced by Bacterial Infection

Pages

  3698-3709

Abstract

 Introduction: Epigenetic mechanisms regulate expression of the genome to generate various cell types during development or coordinate cellular responses to external stimulus. While Epigenetics is of fundamental importance in eukaryotes, it plays a different role in bacteria. This article uncovers the most important recent data on how bacteria can alter Epigenetic marks and can also contribute to and/or result to various diseases. In this review article, Sciencedirect, PubMed, Scopus, Google Scholar databases were used for finding the relevant studies. Research has shown that bacteria can affect the chromatin structure and transcriptional program of host cells by influencing diverse Epigenetic factors (i. e., Histone modifications, DNA methylation, chromatinassociated complexes, and RNA splicing factors). Therefore, bacterial-induced Epigenetic deregulations may affect host cell function either to host defense or to allow pathogen persistence. Hence, pathogenic bacteria can be considered as potential epimutagens able to reshape the epigenome that their effects might leading to cellular dysfunctions, which influenced immunity and might be at the origin of unexplained diseases and this caused presentation or contributed to the development of pathological changes. Conclusion: Epigenetic modifications during development and in response to environmental factors contribute to phenotypic variability and susceptibility to a number of diseases, including infectious diseases, cancers, metabolic and autoimmune disorders.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    Parhamfar, Maryam, & REZAEI, MARZIEH. (2021). Epigenetic Modifications of Host Genes Induced by Bacterial Infection. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, 29(5 ), 3698-3709. SID. https://sid.ir/paper/962580/en

    Vancouver: Copy

    Parhamfar Maryam, REZAEI MARZIEH. Epigenetic Modifications of Host Genes Induced by Bacterial Infection. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;29(5 ):3698-3709. Available from: https://sid.ir/paper/962580/en

    IEEE: Copy

    Maryam Parhamfar, and MARZIEH REZAEI, “Epigenetic Modifications of Host Genes Induced by Bacterial Infection,” JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES, vol. 29, no. 5 , pp. 3698–3709, 2021, [Online]. Available: https://sid.ir/paper/962580/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button