3D ABSORBED DOSE DISTRIBUTIONS MEASUREMENT USING MR IMAGE SIGNAL INTENSITY CHANGES IN FRICKE GEL

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MALEKI N.; RIAHI ALAM N.; AKHLAGHPOUR SH.; ZAHMATKESH M.; ALAHVERDI M.; OGHABIAN M.A.

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Journal: IRANIAN JOURNAL OF MEDICAL PHYSICS Year:2003 | Volume:1 | Issue:1 Page(s): 37-43

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Title

3D ABSORBED DOSE DISTRIBUTIONS MEASUREMENT USING MR IMAGE SIGNAL INTENSITY CHANGES IN FRICKE GEL

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Keywords

MRIQ3

FRICKE GEL DOSIMETRYQ4

3D DOSE MAPPINGQ4

3D TREATMENT PLANNINGQ4

DIFFUSIONQ4

Abstract

3D dose distributions measurement is required for verifying both dose calculation and treatment delivery in complex treatment approaches, such as brachytherapy and conformal radiotherapy. We have proposed an effective method for this verification using MR image signal intensity changes in response to absorbed dose in Fricke gel. Applying a stepped cooling method, we reached a linear response up to 15Gy with a sensitivity of 2.78Gy-1 for optimum imaging parameters TR/TE/500/20, utilizing a 0.5 TMR scanner. Minimium detectable dose was about 1Gy with an uncertainty about 2% for higher doses. Short imaging time of about 2.5 minutes compared to imaging time needed in R1 and R2 based approaches, prevented the DIFFUSION of ferric ions and therefore data distortion was greatly avoided. Our results of 2-D dose-mapping in compliance with Nucletron radiotherapy treatment plans for a cylindrical phantom, showed MRI gel dosimetry based on image intensity changes has a great potential for 3D dose distributions evaluations in medical dosimetry applications with a less complicated implementation and also a reasonable time requirement.

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APA: Copy

MALEKI, N., RIAHI ALAM, N., AKHLAGHPOUR, SH., ZAHMATKESH, M., ALAHVERDI, M., & OGHABIAN, M.A.. (2003). 3D ABSORBED DOSE DISTRIBUTIONS MEASUREMENT USING MR IMAGE SIGNAL INTENSITY CHANGES IN FRICKE GEL. IRANIAN JOURNAL OF MEDICAL PHYSICS, 1(1), 37-43. SID. https://sid.ir/paper/96870/en

Vancouver: Copy

MALEKI N., RIAHI ALAM N., AKHLAGHPOUR SH., ZAHMATKESH M., ALAHVERDI M., OGHABIAN M.A.. 3D ABSORBED DOSE DISTRIBUTIONS MEASUREMENT USING MR IMAGE SIGNAL INTENSITY CHANGES IN FRICKE GEL. IRANIAN JOURNAL OF MEDICAL PHYSICS[Internet]. 2003;1(1):37-43. Available from: https://sid.ir/paper/96870/en

IEEE: Copy

N. MALEKI, N. RIAHI ALAM, SH. AKHLAGHPOUR, M. ZAHMATKESH, M. ALAHVERDI, and M.A. OGHABIAN, “3D ABSORBED DOSE DISTRIBUTIONS MEASUREMENT USING MR IMAGE SIGNAL INTENSITY CHANGES IN FRICKE GEL,” IRANIAN JOURNAL OF MEDICAL PHYSICS, vol. 1, no. 1, pp. 37–43, 2003, [Online]. Available: https://sid.ir/paper/96870/en

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