Para-Bombay B phenotype: a rare ABH blood group variant at tertiary care hospital, Gwalior India

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Sharma Dharmesh Chandra; Rai Sunita; Singhal Sachin; Gupta Prakriti; Sharma Shailendra

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Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN CLINICAL MEDICINE Year:2021 | Volume:9 | Issue:1 Page(s): 0-0

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Title

Para-Bombay B phenotype: a rare ABH blood group variant at tertiary care hospital, Gwalior India

Author(s)

Keywords

H-antigen

Para-Bombay

Secretor status

FUT1

FUT2

Abstract

The H antigen is the precursor substance for A and B antigens formation on red blood cells of an individual, and its absence is termed as H deficient phenotype. The lack of H antigen on both red blood cell (RBCs) and secretions results in a classical Bombay phenotype with anti-H antibodies in serum. If the H antigen is absent on RBCs and present in secretions and plasma, the resulting blood group is the Para-Bombay phenotype. Although, the H gene is genetically absent in Para-Bombay (hh genotype), at least one Se (Secretor) gene is present. Para-Bombay or red blood cell (RBC) H negative secretor individuals may or may not have anti-H in their serum. In both cases, routine blood grouping is O. A blood sample from a 24-year-old female was sent to the blood bank, where the routine grouping revealed O RhD positive. Complete blood grouping by Gel technology revealed that her forward grouping was Oh and reverse grouping was B. Patient is secretor for B and H antigens. The adsorption-elution test is negative. Family grouping was also done to find out compatible blood and her family genesis. Patient blood group was Para-Bombay B. Complete blood grouping (forward and reverse), as well as saliva grouping and adsorption-elution test is advisable when there is a discrepancy in ABH grouping.

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APA: Copy

Sharma, Dharmesh Chandra, Rai, Sunita, Singhal, Sachin, Gupta, Prakriti, & Sharma, Shailendra. (2021). Para-Bombay B phenotype: a rare ABH blood group variant at tertiary care hospital, Gwalior India. JOURNAL OF RESEARCH IN CLINICAL MEDICINE, 9(1), 0-0. SID. https://sid.ir/paper/969028/en

Vancouver: Copy

Sharma Dharmesh Chandra, Rai Sunita, Singhal Sachin, Gupta Prakriti, Sharma Shailendra. Para-Bombay B phenotype: a rare ABH blood group variant at tertiary care hospital, Gwalior India. JOURNAL OF RESEARCH IN CLINICAL MEDICINE[Internet]. 2021;9(1):0-0. Available from: https://sid.ir/paper/969028/en

IEEE: Copy

Dharmesh Chandra Sharma, Sunita Rai, Sachin Singhal, Prakriti Gupta, and Shailendra Sharma, “Para-Bombay B phenotype: a rare ABH blood group variant at tertiary care hospital, Gwalior India,” JOURNAL OF RESEARCH IN CLINICAL MEDICINE, vol. 9, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/969028/en

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