Qualitative and quantitative magnetic resonance imaging assessment of focal liver lesions: a study to evaluate the role of different MRI sequences

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Ashraf Obaid; Naseer Choh; Omair Shah

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Journal Paper

Paper Information

Journal: JOURNAL OF RESEARCH IN CLINICAL MEDICINE Year:2021 | Volume:9 | Issue:1 Page(s): 0-0

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Title

Qualitative and quantitative magnetic resonance imaging assessment of focal liver lesions: a study to evaluate the role of different MRI sequences

Author(s)

Ashraf Obaid | Naseer Choh | Omair Shah | Issue Writer Certificate

Keywords

Magnetic resonance imaging

Diffusion weighted imaging

Apparent diffusion coefficient

Computed tomographic arterial portography

Focal nodular hyperplasia

Hepatocellular carcinoma

Abstract

Introduction: Focal liver lesions have broad differential diagnoses. With its improved soft tissue characterization and newer sequences, Magnetic resonance imaging (MRI) can significantly narrow the differential diagnoses, especially when discriminating benign from malignant lesions. Methods: T1, T1 in-phase and out-of-phase, T2, long TE T2, and diffusion-weighted imaging (DWI) were performed in 159 patients with ultrasound documented focal liver lesion. Qualitative and quantitative assessment of Apparent diffusion coefficient (ADC) values and long TE images were done, and a threshold for differentiating benign from malignant lesions was obtained. The MRI diagnosis was compared with the final diagnosis obtained from histopathology in most cases or the follow-up, and other tests (markers and RBC scan) where histopathology was not available. Sensitivity, specificity, and accuracy of MRI sequences in differentiating various focal lesions were obtained. Results: T1 weighted images were useful for identifying fat, hemorrhage, and iron within the lesions. T2 weighted imaging was able to correctly classify 82. 0% of the malignant lesions and 83. 7% of the benign lesions. Long TE T2 images were highly accurate in distinguishing haemangiomas and cysts from solid lesions. On DWI, 89. 5% (i. e., 60 out of 67) of the lesions were correctly classified as malignant, and 88. 0% (i. e., 81 out of 92) of the lesions were correctly classified as benign. Threshold ADC value of 1. 37 × 10-3 mm2/s is highly accurate for differentiating malignant from benign lesions. Conclusion: DWI is a sine qua non in liver lesion assessment allowing improved detection and characterization. Long TE T2 weighted imaging can accurately detect haemangiomas and cysts, and rule out metastasis.

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APA: Copy

Ashraf, Obaid, Naseer, Choh, & Omair, Shah. (2021). Qualitative and quantitative magnetic resonance imaging assessment of focal liver lesions: a study to evaluate the role of different MRI sequences. JOURNAL OF RESEARCH IN CLINICAL MEDICINE, 9(1), 0-0. SID. https://sid.ir/paper/969723/en

Vancouver: Copy

Ashraf Obaid, Naseer Choh, Omair Shah. Qualitative and quantitative magnetic resonance imaging assessment of focal liver lesions: a study to evaluate the role of different MRI sequences. JOURNAL OF RESEARCH IN CLINICAL MEDICINE[Internet]. 2021;9(1):0-0. Available from: https://sid.ir/paper/969723/en

IEEE: Copy

Obaid Ashraf, Choh Naseer, and Shah Omair, “Qualitative and quantitative magnetic resonance imaging assessment of focal liver lesions: a study to evaluate the role of different MRI sequences,” JOURNAL OF RESEARCH IN CLINICAL MEDICINE, vol. 9, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/969723/en

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