The Eﬀ ect of Ginger and Ondansetron on Post-Operative Nausea and Vomiting in Patients Undergoing Eye Surgery: A Triple-Blind Clinical Trial

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Sedighmarouﬁ Shahnam; Abbaskhani Davanloo Ali; MORADIMAJD PARISA; Samaee Hamidreza; Lavaie mohammad

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Journal: Shiraz E-Medical Journal Year:2021 | Volume:22 | Issue:5 Page(s): 0-0

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Title

The Eﬀ ect of Ginger and Ondansetron on Post-Operative Nausea and Vomiting in Patients Undergoing Eye Surgery: A Triple-Blind Clinical Trial

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Keywords

Nausea

Vomiting

Ginger

Ondansetron

Eye Surgery

Abstract

Background: Postoperative Nausea and Vomiting (PONV) is still a common complication that occurs frequently at the time of recovery from Eye Surgery. Objectives: The present study aimed to compare the eﬀ ect of oral Ondansetron and Ginger on the frequency and severity of postoperative Nausea and Vomiting in patients undergoing Eye Surgery. Methods: A total of 148 patients were randomly assigned to Ginger, Ondansetron, and placebo groups. Group A received a Ginger capsule (1, 000 mg), group B Ondansetron capsule (16 mg), and group C placebo capsule with 30 ml water, one hour before surgery. The frequency of Nausea and Vomiting and the severity of Nausea were recorded immediately after recovery, 1, 2, and 4 hours after recovery. Also, some side eﬀ ects following prescription such as headache, stomach ache, dizziness, and cardiac arrhythmias were recorded. Results: Of the 148 participants, 54% were men, and 46% were women. The average age was in group Ginger (36. 14 2. 17), group Ondansetron (36. 24 2. 49), and group placebo (36. 24 2. 20). There was no signiﬁ cant diﬀ erence in the frequency of Vomiting between the three groups immediately after recovery (P = 0. 19) and 4 hours after surgery (P = 0. 18). However, the frequency of Vomiting in Ginger and Ondansetron groups 1 and 2 hours after the surgery was signiﬁ cantly lower than that in the control group (P = 0. 003). No signiﬁ cant diﬀ erence was observed in the severity of Nausea between the three groups at certain times (P > 0. 05). There was no signiﬁ cant diﬀ erence in terms of the need for injection antiemetic drugs after surgery (P = 0. 2). Conclusions: Ginger and Ondansetron can reduce the frequency of Vomiting. However, Ginger was more eﬀ ective, safer, and less expensive than Ondansetron; therefore, it may be a better substitute for Ondansetron to prevent PONV.

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APA: Copy

Sedighmarouﬁ, Shahnam, Abbaskhani Davanloo, Ali, MORADIMAJD, PARISA, Samaee, Hamidreza, & Lavaie, mohammad. (2021). The Eﬀ ect of Ginger and Ondansetron on Post-Operative Nausea and Vomiting in Patients Undergoing Eye Surgery: A Triple-Blind Clinical Trial. SHIRAZ E MEDICAL JOURNAL, 22(5), 0-0. SID. https://sid.ir/paper/972835/en

Vancouver: Copy

Sedighmarouﬁ Shahnam, Abbaskhani Davanloo Ali, MORADIMAJD PARISA, Samaee Hamidreza, Lavaie mohammad. The Eﬀ ect of Ginger and Ondansetron on Post-Operative Nausea and Vomiting in Patients Undergoing Eye Surgery: A Triple-Blind Clinical Trial. SHIRAZ E MEDICAL JOURNAL[Internet]. 2021;22(5):0-0. Available from: https://sid.ir/paper/972835/en

IEEE: Copy

Shahnam Sedighmarouﬁ, Ali Abbaskhani Davanloo, PARISA MORADIMAJD, Hamidreza Samaee, and mohammad Lavaie, “The Eﬀ ect of Ginger and Ondansetron on Post-Operative Nausea and Vomiting in Patients Undergoing Eye Surgery: A Triple-Blind Clinical Trial,” SHIRAZ E MEDICAL JOURNAL, vol. 22, no. 5, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/972835/en

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