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Title

The Effect of Berberis vulgaris (Barberry Fruit) on a Component of Metabolic Syndrome: A Randomized Clinical Trial

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Abstract

 Background: The Metabolic Syndrome is associated with increased risks of cardiovascular diseases and diabetes mellitus. Objectives: As alternative medicine emerged worldwide, this study aimed to evaluate the efficacy of Berberis vulgaris (barberry fruit) in the treatment of Metabolic Syndrome. Methods: This is a randomized, placebo controlled, double-blind, trial with two treatment arms. A total of 60 patients with Metabolic Syndrome were randomly assigned to receive barberry or placebo tablets (one 550 mg tablets per day for 3 weeks). Total cholesterol, LDL, HDL, triglyceride, fasting blood sugar and Hematocrit were measured before and after 21 days of treatment. Data were analyzed using Mann-Whitney U and paired t-test by SPSS (V. 15) software. P-values < 0. 05 were considered to be significant. Results: In the barberry group, there was a significant decrease in systolic blood pressure (pre-treatment 123. 1  13. 1 vs. posttreatment 117. 7  13. 2, P-value = 0. 04), waist circumference (pre-treatment 105. 9  7. 5 vs. post-treatment105  7. 7, P-value = 0. 04) and Hematocrit (pre-treatment 45  3. 6 vs. post-treatment 43. 5  2. 7, P-value = 0. 004) but other parameters did not change significantly. Serum cholesterol was significantly reduced after intervention in the barberry group (-17  61. 1 vs. 23. 6  45, P-value = 0. 02). Conclusions: We observed a significant effect of barberry on systolic blood pressure and waist circumference. Further studies with larger samples are needed to longitudinally investigate the effect of Metabolic Syndrome.

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    APA: Copy

    KERMANI, TAYYEBEH, KAZEMI, TOBA, Molki, Somayye, Ilkhani, Khadije, & SHARIFZADEH, GHOLAMREZA. (2020). The Effect of Berberis vulgaris (Barberry Fruit) on a Component of Metabolic Syndrome: A Randomized Clinical Trial. MODERN CARE JOURNAL, 17(2), 0-0. SID. https://sid.ir/paper/974681/en

    Vancouver: Copy

    KERMANI TAYYEBEH, KAZEMI TOBA, Molki Somayye, Ilkhani Khadije, SHARIFZADEH GHOLAMREZA. The Effect of Berberis vulgaris (Barberry Fruit) on a Component of Metabolic Syndrome: A Randomized Clinical Trial. MODERN CARE JOURNAL[Internet]. 2020;17(2):0-0. Available from: https://sid.ir/paper/974681/en

    IEEE: Copy

    TAYYEBEH KERMANI, TOBA KAZEMI, Somayye Molki, Khadije Ilkhani, and GHOLAMREZA SHARIFZADEH, “The Effect of Berberis vulgaris (Barberry Fruit) on a Component of Metabolic Syndrome: A Randomized Clinical Trial,” MODERN CARE JOURNAL, vol. 17, no. 2, pp. 0–0, 2020, [Online]. Available: https://sid.ir/paper/974681/en

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