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Title

The Predictive Value of Mean Platelet Volume for Liver Fibrosis in Children With Chronic Liver Diseases

Pages

  131-135

Abstract

 Introduction: Almost all causes of chronic liver damage can culminate in Liver fibrosis and ultimately cirrhosis. Studies have suggested a relationship between Mean platelet volume (MPV) and Liver fibrosis; however, this needs confirmation by further studies. We here assessed the predictive value of MPV for Liver fibrosis in children with Chronic liver diseases. Methods: In this study, children <18 years old with Chronic liver diseases referred to the Nemazee Hospital of Shiraz during 2013-2016 were studied. The patients underwent liver biopsy for assessing Liver fibrosis. Statistical analyses were conducted in SPSS 23. Results: From 368 studied children, 52. 2% were boys. The patients’ mean age was 4. 5± 3. 9 years old. Most patients had grade 6 fibrosis (36. 7%). Cryptogenic (42. 7%) was the most common cause of Chronic liver disease, and jaundice was the most prevalent clinical presentation (53%). There was a significant association between the Liver fibrosis and MPV (P = 0. 025). Conclusion: MPV was significantly different between patients with different severities of Liver fibrosis. However, assigning an appropriate cut off value to distinguish different degrees of fibrosis requires more studies.

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    APA: Copy

    DEHGHANI, SEYED MOHSEN, BORDBAR, MOHAMMAD REZA, Salimi, Rezvan, SHAHRAMIAN, IRAJ, MIRZAEI, HADI, GHOLAMI, SIAVASH, SHARAFI, FATEMEH, BAZI, ALI, ATAOLLAHI, MARYAM, Fazeli, Fatemeh, & Hamzeloo, Samaneh. (2020). The Predictive Value of Mean Platelet Volume for Liver Fibrosis in Children With Chronic Liver Diseases. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, 5(4), 131-135. SID. https://sid.ir/paper/975140/en

    Vancouver: Copy

    DEHGHANI SEYED MOHSEN, BORDBAR MOHAMMAD REZA, Salimi Rezvan, SHAHRAMIAN IRAJ, MIRZAEI HADI, GHOLAMI SIAVASH, SHARAFI FATEMEH, BAZI ALI, ATAOLLAHI MARYAM, Fazeli Fatemeh, Hamzeloo Samaneh. The Predictive Value of Mean Platelet Volume for Liver Fibrosis in Children With Chronic Liver Diseases. INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE[Internet]. 2020;5(4):131-135. Available from: https://sid.ir/paper/975140/en

    IEEE: Copy

    SEYED MOHSEN DEHGHANI, MOHAMMAD REZA BORDBAR, Rezvan Salimi, IRAJ SHAHRAMIAN, HADI MIRZAEI, SIAVASH GHOLAMI, FATEMEH SHARAFI, ALI BAZI, MARYAM ATAOLLAHI, Fatemeh Fazeli, and Samaneh Hamzeloo, “The Predictive Value of Mean Platelet Volume for Liver Fibrosis in Children With Chronic Liver Diseases,” INTERNATIONAL JOURNAL OF BASIC SCIENCE IN MEDICINE, vol. 5, no. 4, pp. 131–135, 2020, [Online]. Available: https://sid.ir/paper/975140/en

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