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Information Journal Paper

Title

A Comparative Study on the Eff ects of Ketofol, Dexmedetomidine, and Isofol in Anesthesia of Candidates for Dilatation and Curettage

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  0-0

Abstract

 Background: Dilatation and Curettage (D & C) is one of the relatively common surgeries among women. Familiarity with the analgesics, along with their diff erent uses and specifi c characteristics, can help to determine the best and most appropriate drug to control pain in the patients. Objectives: This study aimed to compare the eff ects of ketofol, Dexmedetomidine, and isofol in anesthesia of candidates for D & C. Methods: In this double-blind clinical trial, 150 candidates for D & C surgeries with ASA class 1 and 2 were included. Patients were randomly divided into three groups. The fi rst group received Ketamine + Propofol, the second group received Dexmedetomidine, and the third group received isofol (isofl urane + Propofol). Any hemodynamic changes or respiratory disorders, including apnea or hypoventilation, drop in the level of blood oxygen saturation, and the need for respiratory support, were recorded and compared. Results: Hypoventilation was observed in 47 patients in isofol group, 18 in the Dexmedetomidine group, and 42 in ketofol group. Also, 48 patients in the isofol group, eight in the Dexmedetomidine group, and 33 in the ketofol group experienced apnea. Moreover, 17 patients in the Dexmedetomidine group, 35 in the ketofol group, and eight in the isofol group experienced bradycardia. The rate of bradycardia was signifi cantly higher in the Dexmedetomidine group (70%) compared to the other two groups, and the rate of hypotension was signifi cantly higher in the isofol group (P = 0. 001). Conclusions: According to the results, Dexmedetomidine was associated with fewer complications during general anesthesia in D & C surgery.

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    APA: Copy

    Yousefian, Mahzad, MOHAMMADIAN ERDI, ALI, & HAGHSHENAS, negin. (2021). A Comparative Study on the Eff ects of Ketofol, Dexmedetomidine, and Isofol in Anesthesia of Candidates for Dilatation and Curettage. ANESTHESIOLOGY AND PAIN MEDICINE, 11(6), 0-0. SID. https://sid.ir/paper/976237/en

    Vancouver: Copy

    Yousefian Mahzad, MOHAMMADIAN ERDI ALI, HAGHSHENAS negin. A Comparative Study on the Eff ects of Ketofol, Dexmedetomidine, and Isofol in Anesthesia of Candidates for Dilatation and Curettage. ANESTHESIOLOGY AND PAIN MEDICINE[Internet]. 2021;11(6):0-0. Available from: https://sid.ir/paper/976237/en

    IEEE: Copy

    Mahzad Yousefian, ALI MOHAMMADIAN ERDI, and negin HAGHSHENAS, “A Comparative Study on the Eff ects of Ketofol, Dexmedetomidine, and Isofol in Anesthesia of Candidates for Dilatation and Curettage,” ANESTHESIOLOGY AND PAIN MEDICINE, vol. 11, no. 6, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/976237/en

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