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Information Journal Paper

Title

PREPARATION AND QUALITY CONTROL OF RADIOLABELLED COBALT-57 BLEOMYCINS FOR ONCOLOGICAL STUDIES

Pages

  1-6

Keywords

SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY (SPECT)Q3

Abstract

 [55Co] BLEOMYCIN has been widely used in oncological studies. Due to relative short half life of cobalt-55, optimization and feasibility studies for determination of the best labeling conditions is preferably performed using COBALT-57. In this study, the optimization of complexation conditions for time, temperature and ligand concentration were performed. The best labeling yield was obtained at room temperature in pH of 4-7, using 0.4 mCi of 57CoCl2 with 0.3mg of BLM in 30 minutes. The final radiopharmaceutical solution underwent common QUALITY CONTROL tests, validating our future studies for animal scanning studies using [55Co] BLEOMYCIN complex.

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  • Cite

    APA: Copy

    JALILIAN, AMIR REZA, ROUSHAN FARZAD, P., MOAFIAN, J., ENSAF, M.R., & SABET, MAHSHID. (2006). PREPARATION AND QUALITY CONTROL OF RADIOLABELLED COBALT-57 BLEOMYCINS FOR ONCOLOGICAL STUDIES. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, -(3 (38)), 1-6. SID. https://sid.ir/paper/97871/en

    Vancouver: Copy

    JALILIAN AMIR REZA, ROUSHAN FARZAD P., MOAFIAN J., ENSAF M.R., SABET MAHSHID. PREPARATION AND QUALITY CONTROL OF RADIOLABELLED COBALT-57 BLEOMYCINS FOR ONCOLOGICAL STUDIES. JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY[Internet]. 2006;-(3 (38)):1-6. Available from: https://sid.ir/paper/97871/en

    IEEE: Copy

    AMIR REZA JALILIAN, P. ROUSHAN FARZAD, J. MOAFIAN, M.R. ENSAF, and MAHSHID SABET, “PREPARATION AND QUALITY CONTROL OF RADIOLABELLED COBALT-57 BLEOMYCINS FOR ONCOLOGICAL STUDIES,” JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY, vol. -, no. 3 (38), pp. 1–6, 2006, [Online]. Available: https://sid.ir/paper/97871/en

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