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Information Journal Paper

Title

Clinical Scenario and Imaging with Illustrations of Giant Cell Tumor of Bone: A Retrospective Analysis

Pages

  60-66

Abstract

 Background: The giant cell tumour of the bone has a spectrum of clinical-radiological presentation. This study aims to describe this varied presentation in our institution. Methods: This retrospective study was conducted on twenty-nine pathologically labelled cases of giant cell tumours of the bone. The medical records for their clinical presentation and diagnostic imaging studies were studied and evaluated. Results: Mean age of the patients at presentation was 35. 3± 12. 9 years. Pain, local swelling and restricted joint function were seen in 93 %, 58. 6 % and 52 % patients, respectively. The cortical breach was seen in 15 (51. 7 %) and 22 (75. 9 %) lesions on plain radiographs and CT images, respectively. 14(48. 3 %) cases had soft tissue invasion on MRI at presentation. 26 (89. 7 %) lesions were located within 1 cm from the articular cartilage. The solid tumour component was hypo to iso-intense in signal intensity in 27 (93. 1 %) lesions in T1 weighted and 21 (72. 4 %) in T2 weighted images. 14 (48. 3 %) had hyperintense cystic areas, and Fluid-Fluid levels, suggestive of aneurysmal bone cysts, were seen in 4 (13. 8 %) cases on T2 weighted images. Hypo-echoic nodular areas in solid tumour component, suggestive of Hemosiderin deposits, were present in 3 (10. 3 %) lesions on T1 and T2 weighted images. Conclusion: The tumour classically presents as an epiphysial-metaphyseal, eccentric, expansile, lytic lesion in a skeletally mature patient. The MRI picture is variable and the surgeon should have a sound knowledge of these variations to obtain a biopsy sample from a proper site of the lesion and to avoid misdiagnosis especially of a primary ABC.

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    • Cite

    APA: Copy

    ALI, NADEEM, Ahmad Shah, Azad, Rakshan, Ibreez, Kawoosa, Altaf Ahmad, & Mumtaz, Mohammad Umar. (2022). Clinical Scenario and Imaging with Illustrations of Giant Cell Tumor of Bone: A Retrospective Analysis. THE ARCHIVES OF BONE AND JOINT SURGERY, 10(1), 60-66. SID. https://sid.ir/paper/979332/en

    Vancouver: Copy

    ALI NADEEM, Ahmad Shah Azad, Rakshan Ibreez, Kawoosa Altaf Ahmad, Mumtaz Mohammad Umar. Clinical Scenario and Imaging with Illustrations of Giant Cell Tumor of Bone: A Retrospective Analysis. THE ARCHIVES OF BONE AND JOINT SURGERY[Internet]. 2022;10(1):60-66. Available from: https://sid.ir/paper/979332/en

    IEEE: Copy

    NADEEM ALI, Azad Ahmad Shah, Ibreez Rakshan, Altaf Ahmad Kawoosa, and Mohammad Umar Mumtaz, “Clinical Scenario and Imaging with Illustrations of Giant Cell Tumor of Bone: A Retrospective Analysis,” THE ARCHIVES OF BONE AND JOINT SURGERY, vol. 10, no. 1, pp. 60–66, 2022, [Online]. Available: https://sid.ir/paper/979332/en

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