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Information Journal Paper

Title

Intranasal Ketamine Versus Intravenous Ketorolac for Pain Control in the Renal Colic: A Randomized Clinical Trial Study

Pages

  0-0

Abstract

 Background: Renal Colic is one of the most common complaints among patients referring to the emergency department (ED). Non-steroidal anti-infl ammatory drugs (NSAIDs) and opioids are gold standards to refereeing patients. Objectives: The aim of this study was to evaluate the eff ects of intranasal Ketamine on pain control versus Ketorolac. Methods: In this randomized clinical trial (RCT), the patients were randomly assigned into two groups. Ketorolac 30 mg was given intravenously to all patients in the control group, the patients in intervention group received 1 mg/kg drops of Ketamine intranasally. Pain severity, vital signs, and adverse events (AEs) were recorded after 60 minutes post-dose. Results: A total of 100 patients were enrolled in this study. The mean visual analog scale (VAS) score after the fi rst 5 minutes was lower in the intranasal Ketamine group compared to control (5  2. 26 vs. 8. 62  0. 49, respectively; P < 0. 001), which remained signifi cant at the end of 60th minutes (P < 0. 001). Moreover, additional analgesics administration was higher in intravenous Ketorolac than intranasal Ketamine (22 vs 0%), which was signifi cantly diff erent (P = 0. 001). Patients’ satisfaction was higher in the intranasal Ketamine group compared to control (3. 56  0. 35 vs. 1. 82  0. 98, respectively; P < 0. 001). Conclusions: Intranasal Ketamine was benefi cial in controlling Renal Colic-induced pain, which could be prescribed as a treatment instead of normal treatment. It can rapidly improve pain relief in the short term, has lower AEs, and increases the patients’ satisfaction.

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    APA: Copy

    KHAVANIN, ALI, Moezzi, Meisam, MOTAMED, HASSAN, Parozan, Samaneh, & Hosseini, Abdolreza. (2021). Intranasal Ketamine Versus Intravenous Ketorolac for Pain Control in the Renal Colic: A Randomized Clinical Trial Study. JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE, 10(3), 0-0. SID. https://sid.ir/paper/979359/en

    Vancouver: Copy

    KHAVANIN ALI, Moezzi Meisam, MOTAMED HASSAN, Parozan Samaneh, Hosseini Abdolreza. Intranasal Ketamine Versus Intravenous Ketorolac for Pain Control in the Renal Colic: A Randomized Clinical Trial Study. JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE[Internet]. 2021;10(3):0-0. Available from: https://sid.ir/paper/979359/en

    IEEE: Copy

    ALI KHAVANIN, Meisam Moezzi, HASSAN MOTAMED, Samaneh Parozan, and Abdolreza Hosseini, “Intranasal Ketamine Versus Intravenous Ketorolac for Pain Control in the Renal Colic: A Randomized Clinical Trial Study,” JUNDISHAPUR JOURNAL OF CHRONIC DISEASE CARE, vol. 10, no. 3, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/979359/en

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