The Relationship Between Malnutrition and Liver Enzymes in Hospitalized Children in Zahedan: A Case-control Study

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KARAJIBANI MANSOUR; MONTAZERIFAR FARZANEH; Hosseini Razieh; Suni Fatemeh; Dashipour Ali Reza; Fadaaei Mokhtarkanlo Mahshid

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Journal Paper

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Journal: Zahedan Journal of Research in Medical Sciences Year:2021 | Volume:23 | Issue:1 Page(s): 0-0

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Title

The Relationship Between Malnutrition and Liver Enzymes in Hospitalized Children in Zahedan: A Case-control Study

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Keywords

Malnutrition

Enzymes

Alanine Aminotransferase

Aspartate Aminotransferase

Alkaline Phosphatase

Abstract

Background: Malnutrition causes nutritional, metabolism, and biochemical disorders and finally leads to mortality. Several studies have highlighted that serum liver Enzymes are increased in patients with Malnutrition. Objectives: This study aimed to evaluate the relationship between Malnutrition and liver Enzymes in hospitalized children in Zahedan. Methods: This case-control study was conducted among 145 hospitalized children under six years old, including 74 cases and 71 controls. The case group was diagnosed with Malnutrition according to weight for age indices (Z-Score <-2SD), and controls were determined based on the following indices (Z-Score >-2SD) of classification of WHO2006 growth standards. Serum was isolated after taking blood from the samples. Then liver Enzymes, including AST, ALP, and ALT, were measured by spectrophotometric method. Results: A total of 145 subjects were enrolled that consisted of 74 cases and 71 controls. No significant difference was observed in serum liver markers, including AST, ALT, and ALP between the two groups, However, the level of AST, ALT, and ALP was higher than the standard level. There was a significant correlation between AST with ALT (r = 0. 74, P < 0. 001), and ALP (r = 0. 27, P = 0. 03). Conclusions: The findings indicated that there was no significant alteration in enzyme markers in the two groups. However, AST and ALT levels increased, and ALP levels decreased compared with the control. Different degrees of Malnutrition, including mild, moderate, and severe, can probably change the levels of hepatic Enzymes in under-nourished children. Alteration of these liver Enzymes could be due to the metabolic modification, which can be the result of protein deficiency.

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APA: Copy

KARAJIBANI, MANSOUR, MONTAZERIFAR, FARZANEH, Hosseini, Razieh, Suni, Fatemeh, Dashipour, Ali Reza, & Fadaaei Mokhtarkanlo, Mahshid. (2021). The Relationship Between Malnutrition and Liver Enzymes in Hospitalized Children in Zahedan: A Case-control Study. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), 23(1), 0-0. SID. https://sid.ir/paper/979973/en

Vancouver: Copy

KARAJIBANI MANSOUR, MONTAZERIFAR FARZANEH, Hosseini Razieh, Suni Fatemeh, Dashipour Ali Reza, Fadaaei Mokhtarkanlo Mahshid. The Relationship Between Malnutrition and Liver Enzymes in Hospitalized Children in Zahedan: A Case-control Study. ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH)[Internet]. 2021;23(1):0-0. Available from: https://sid.ir/paper/979973/en

IEEE: Copy

MANSOUR KARAJIBANI, FARZANEH MONTAZERIFAR, Razieh Hosseini, Fatemeh Suni, Ali Reza Dashipour, and Mahshid Fadaaei Mokhtarkanlo, “The Relationship Between Malnutrition and Liver Enzymes in Hospitalized Children in Zahedan: A Case-control Study,” ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES (TABIB-E-SHARGH), vol. 23, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/979973/en

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