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Information Journal Paper

Title

Association of Microalbuminuria and Bevacizumab Therapy Outcomes in Diabetic Retinopathy Patients

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  0-0

Abstract

 Background: Diabetic Retinopathy (DR) is a visual impairment-related eye disease developed by long-term hyperglycemic status. Diabetic condition in DR patients leads to diabetic organopathies (e. g., renal failure). Albuminuria, as a hallmark of renal failure, can be correlated with visual indicators in DR patients. Objectives: This study aimed to investigate the role of albuminuria status in Visual Acuity (VA) and Bevacizumab therapy outcomes in DR patients. Methods: In this retrospective study, 48 DR patients were admitted to the Ophthalmology Center of Ayatollah Rouhani Hospital, affi liated with Babol University of Medical Sciences, Babol, Iran. The retinopathy status and VA were identifi ed before and after treatment through 45 days of Bevacizumab therapy. In addition, fast blood sugar, hemoglobin A1c, urine albumin, and urine Creatinine were evaluated using standard laboratory methods. Results: The VA value before treatment in microalbuminuric DR patients (0. 106  0. 036) was signifi cantly lower than nonmicroalbuminuric DR patients (0. 347  0. 286; P < 0. 001). Furthermore, VA value after treatment in microalbuminuric DR patients (0. 115  0. 071) was signifi cantly lower than non-microalbuminuric DR patients (0. 355  0. 272; P < 0. 001). There was no signifi cant diff erence in the percentage of VA increase between microalbuminuric and non-microalbuminuric patients. Moreover, the albumin-to-Creatinine ratio (ACR) was correlated with a lower VA level before and after treatment (P < 0. 001 for both). There was no correlation between the percentage of VA increase with ACR, albumin, and Creatinine. Conclusions: The current study results showed that diff erent VA before and after Bevacizumab therapy status was correlated with Microalbuminuria status. Additionally, Microalbuminuria status did not aff ect the percentage of VA increase in the treatment of DR patients.

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    APA: Copy

    RASOULINEJAD, SEYED AHMAD. (2022). Association of Microalbuminuria and Bevacizumab Therapy Outcomes in Diabetic Retinopathy Patients. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, 14(1), 0-0. SID. https://sid.ir/paper/983358/en

    Vancouver: Copy

    RASOULINEJAD SEYED AHMAD. Association of Microalbuminuria and Bevacizumab Therapy Outcomes in Diabetic Retinopathy Patients. THE JOURNAL OF NEPHRO-UROLOGY MONTHLY[Internet]. 2022;14(1):0-0. Available from: https://sid.ir/paper/983358/en

    IEEE: Copy

    SEYED AHMAD RASOULINEJAD, “Association of Microalbuminuria and Bevacizumab Therapy Outcomes in Diabetic Retinopathy Patients,” THE JOURNAL OF NEPHRO-UROLOGY MONTHLY, vol. 14, no. 1, pp. 0–0, 2022, [Online]. Available: https://sid.ir/paper/983358/en

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