STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L. ) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH

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Amini Nooshin; SHIRAVI ABDOLHOSSEIN; MIRAZI NASER; HOJATI VIDA; Abbasalipourkabir Roghayeh

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Journal: Studies in Medical Sciences Year:2020 | Volume:31 | Issue:9 Page(s): 650-657

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Title

STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L. ) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH

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Keywords

Raspberry extract

Spermatogenesis

Diabetes

Rat

Abstract

Background & Aims: The aim of this study was to evaluate the protective effects of raspberry fruit extract (Rubus fruticosus L. ) on LH, FSH, testosterone serum levels, and number and percentage of sperm motility in male diabetic Rats induced with streptozotocin. Materials & Methods: In this experimental study, 50 Wistar male Rats were used and divided into five groups: (control), diabetic (STZ, 55mg/kg, i. p), and treatment groups (DM + raspberry fruit extract: 50, 100, 200 mg/kg/day, 4 weeks). At the end of experiments, the LH, FSH and testosterone serum levels and the number and percentage of sperm motility were examined. The data were statistically analyzed by ANOVA test. Results: The LH and FSH serum levels increased significantly in DM group compared with other groups (p<0. 05). After treatment with raspberry fruit extract, the LH and FSH serum levels decreased significantly compared with DM group (p<0. 05). The testosterone serum level and the number and percentage of sperm motility decreased significantly in the DM group (p<0. 05). The use of raspberry fruit extract significantly increased testosterone serum level and the number and percentage of sperm motility in treatment groups (p<0. 05). Conclusion: Our results showed that raspberry fruit extract increased testosterone hormone in DM Rats, and also improved Spermatogenesis and amelioRating pituitary-gonadal axis function.

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APA: Copy

Amini, Nooshin, SHIRAVI, ABDOLHOSSEIN, MIRAZI, NASER, HOJATI, VIDA, & Abbasalipourkabir, Roghayeh. (2020). STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L. ) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), 31(9 ), 650-657. SID. https://sid.ir/paper/984455/en

Vancouver: Copy

Amini Nooshin, SHIRAVI ABDOLHOSSEIN, MIRAZI NASER, HOJATI VIDA, Abbasalipourkabir Roghayeh. STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L. ) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH. STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES)[Internet]. 2020;31(9 ):650-657. Available from: https://sid.ir/paper/984455/en

IEEE: Copy

Nooshin Amini, ABDOLHOSSEIN SHIRAVI, NASER MIRAZI, VIDA HOJATI, and Roghayeh Abbasalipourkabir, “STUDY OF PROTECTIVE EFFECTS OF RASPBERRY FRUIT EXTRACT (RUBUS FRUTICOSUS L. ) ON CHANGES IN GONADOTROPIN HORMONES, TESTOSTERONE AND SPERMATOGENESIS IN MALE DIABETIC RATS INDUCED WITH,” STUDIES IN MEDICAL SCIENCE (THE JOURNAL OF URMIA UNIVERSITY OF MEDICAL SCINCES), vol. 31, no. 9 , pp. 650–657, 2020, [Online]. Available: https://sid.ir/paper/984455/en

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