EFFICACY OF OMEGA-3 ON HOT FLUSH IN PERIMENOPAUSAL WOMEN VERSUS PLACEBO

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GHASEMI AFSANEH; REZAEI AZADEH; KHATIBI ALI; JAHANLU ATUSA

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Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2012 | Volume:22 | Issue:3 (69) Page(s): 221-225

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Title

EFFICACY OF OMEGA-3 ON HOT FLUSH IN PERIMENOPAUSAL WOMEN VERSUS PLACEBO

Author(s)

GHASEMI AFSANEH | REZAEI AZADEH | KHATIBI ALI | JAHANLU ATUSA | Issue Writer Certificate

Keywords

FLUSHINGQ3

MENOPAUSEQ2

OMEGA-3Q2

Abstract

Background: Regarding complications and contraindications of hormone replacement therapy, non-hormonal treatment of postmenopausal symptoms is a subject of great interest today. This study was designed to evaluate the efficacy of omega– 3 in relieving menopausal symptoms, including hot flush.Materials and methods: Sixty healthy MENOPAUSE women suffering from hot flush beginning about 12 months ago (6 to 18 months) were recruited to this placebo– omega– 3 double– blind clinical trial (30 subjects each group). MENOPAUSE rating scale (MRS) was applied and hot flash attacks were registered. Patients took the drug daily for 3 months (omega -3, 1000mg daily and placebo with the same appearance once daily) and the severity and rate of attacks were obtained before beginning of treatment and monthly during the study and then at the third and sixth months after ending the treatment.Results: At the beginning study, there were no significant differences between two groups regarding age, MENOPAUSE duration, and severity and number of hot flashes. After 3 month, omega– 3 significantly decreased severity of attacks compared with placebo (P=0.005). But, 3 and 6 months after the end of treatment, severity of attacks were similar in both groups.Conclusion: Omega- 3 with dose of 1000mg daily decreases severity of hot flash attacks, but it has no effects on number of attacks.

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APA: Copy

GHASEMI, AFSANEH, REZAEI, AZADEH, KHATIBI, ALI, & JAHANLU, ATUSA. (2012). EFFICACY OF OMEGA-3 ON HOT FLUSH IN PERIMENOPAUSAL WOMEN VERSUS PLACEBO. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 22(3 (69)), 221-225. SID. https://sid.ir/paper/98630/en

Vancouver: Copy

GHASEMI AFSANEH, REZAEI AZADEH, KHATIBI ALI, JAHANLU ATUSA. EFFICACY OF OMEGA-3 ON HOT FLUSH IN PERIMENOPAUSAL WOMEN VERSUS PLACEBO. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2012;22(3 (69)):221-225. Available from: https://sid.ir/paper/98630/en

IEEE: Copy

AFSANEH GHASEMI, AZADEH REZAEI, ALI KHATIBI, and ATUSA JAHANLU, “EFFICACY OF OMEGA-3 ON HOT FLUSH IN PERIMENOPAUSAL WOMEN VERSUS PLACEBO,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 22, no. 3 (69), pp. 221–225, 2012, [Online]. Available: https://sid.ir/paper/98630/en

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