Exploring cytotoxic drugs residues in hospital effluents: a narrative review

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HASHEMIAN FARSHAD; Roohi Elnaz

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Journal Paper

Paper Information

Journal: MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY Year:2020 | Volume:29 | Issue:4 Page(s): 284-295

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Title

Exploring cytotoxic drugs residues in hospital effluents: a narrative review

Author(s)

HASHEMIAN FARSHAD | Roohi Elnaz | Issue Writer Certificate

Keywords

Hospital effluentsQ1

Antineoplastic drugsQ1

Cytotoxic drugsQ1

Hospital wasteQ2

Abstract

Background: Cytotoxic waste management is one of the significant issues in healthcare system. The aim of the present study was to review studies conducted on investigation of possible levels of cytotoxic drug residues in Hospital effluents. Materials and methods: All peer-reviewed journal articles on investigation of possible levels of Cytotoxic drugs residues in Hospital effluents which were published before May 2019 were investigated. 51 publications which were mostly published between 2011 and 2016 were included. Results: Anticancer medication continue to enter Hospital effluents and urbane wastewaters. Hospital effluents seem to be one of the main sources of water contamination in this regard. Cytotoxic drugs and their metabolites are detected in Hospital effluents in different countries across the globe. Platinum-based Antineoplastic drugs, methotrexate, cyclophosphamide, ifosfamide and tamoxifen were found with higher concentrations across different studies. Conclusion: Hospital waste management is one of the most important issues in health care system. According to the results of the present study, Cytotoxic drugs residues are detected in the effluents of oncology wards of the investigated hospitals. Therefore, establishment of strict rules and regulations, provision of cytotoxic waste disposal and removal for the purpose of inactivating Cytotoxic drugs in Hospital effluents prior to entrance of the effluents to the sewage treatment systems is mandatory.

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APA: Copy

HASHEMIAN, FARSHAD, & Roohi, Elnaz. (2020). Exploring cytotoxic drugs residues in hospital effluents: a narrative review. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, 29(4 ), 284-295. SID. https://sid.ir/paper/98677/en

Vancouver: Copy

HASHEMIAN FARSHAD, Roohi Elnaz. Exploring cytotoxic drugs residues in hospital effluents: a narrative review. MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY[Internet]. 2020;29(4 ):284-295. Available from: https://sid.ir/paper/98677/en

IEEE: Copy

FARSHAD HASHEMIAN, and Elnaz Roohi, “Exploring cytotoxic drugs residues in hospital effluents: a narrative review,” MEDICAL SCIENCES JOURNAL OF ISLAMIC AZAD UNIVERSITY, vol. 29, no. 4 , pp. 284–295, 2020, [Online]. Available: https://sid.ir/paper/98677/en

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