STUDY OF COAGULOPATHY AND ITS RISK FACTORS IN CHILDREN ON PROLONGED ANTIBIOTIC THERAPY ADMITTED INTO RASOUL-E-AKRAM HOSPITAL, 2002-2003

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EHSANIPOUR F.; ZARIFIAN D.

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Journal: Razi Journal of Medical Sciences Year:2005 | Volume:12 | Issue:47 Page(s): 11-17

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Title

STUDY OF COAGULOPATHY AND ITS RISK FACTORS IN CHILDREN ON PROLONGED ANTIBIOTIC THERAPY ADMITTED INTO RASOUL-E-AKRAM HOSPITAL, 2002-2003

Author(s)

EHSANIPOUR F. | ZARIFIAN D. | Issue Writer Certificate

Keywords

ANTIBIOTIC THERAPYQ4

VITAMIN KQ2

COAGULOPATHYQ2

Abstract

Background & Objective: VITAMIN K deficiency is one of the commonest causes of COAGULOPATHY and bleeding in patients on prolonged ANTIBIOTIC THERAPY. This study was conducted to evaluate the status of VITAMIN K deficiency in hospitalized children on prolonged ANTIBIOTIC THERAPY and its role in reversing the COAGULOPATHY. Method: A prospective non-randomized, cross-sectional study was conducted on children on prolonged ANTIBIOTIC THERAPY whose ages ranged from 3 months to 16 years old. These children were under treatment in the ward and pediatric I.C.U. Results: In this study, 25 out of 81 children (30.86%) were hypoprothrombinemic. Children ranging from 3 months to 1 year old developed significant COAGULOPATHY as compared to other age groups(33.33%). Coagulation abnormalities were also seen to be more in children with severe grades of malnutrition(50%), on a more prolonged(>10 days) course of ANTIBIOTIC THERAPY(36.36%), on β -lactam+vancomycin combination therapy (40.54%), in children who were NPO(45.45%) and in children who were critically ill in the intensive care unit(I.C.U)(47.61%). Conclusion: we suggest VITAMIN K prophylaxis in patients on prolonged ANTIBIOTIC THERAPY (>10 days) especially the patients suffering from mentioned conditions to prevent mortality and morbidity.

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APA: Copy

EHSANIPOUR, F., & ZARIFIAN, D.. (2005). STUDY OF COAGULOPATHY AND ITS RISK FACTORS IN CHILDREN ON PROLONGED ANTIBIOTIC THERAPY ADMITTED INTO RASOUL-E-AKRAM HOSPITAL, 2002-2003. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), 12(47), 11-17. SID. https://sid.ir/paper/9905/en

Vancouver: Copy

EHSANIPOUR F., ZARIFIAN D.. STUDY OF COAGULOPATHY AND ITS RISK FACTORS IN CHILDREN ON PROLONGED ANTIBIOTIC THERAPY ADMITTED INTO RASOUL-E-AKRAM HOSPITAL, 2002-2003. RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2005;12(47):11-17. Available from: https://sid.ir/paper/9905/en

IEEE: Copy

F. EHSANIPOUR, and D. ZARIFIAN, “STUDY OF COAGULOPATHY AND ITS RISK FACTORS IN CHILDREN ON PROLONGED ANTIBIOTIC THERAPY ADMITTED INTO RASOUL-E-AKRAM HOSPITAL, 2002-2003,” RAZI JOURNAL OF MEDICAL SCIENCES (JOURNAL OF IRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 12, no. 47, pp. 11–17, 2005, [Online]. Available: https://sid.ir/paper/9905/en

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