Clinco-etiological Profile and Predictors of Outcome of Neonatal Seizures: A Prospective Observational Study from Egypt

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Rateb Abd Almonaem Eman; Shaheen Dabour Ahmed; Ahmed Elawady Mona; Mohamed Abdel Haie Omima

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF NEONATOLOGY Year:2022 | Volume:13 | Issue:2 Page(s): 22-31

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

Clinco-etiological Profile and Predictors of Outcome of Neonatal Seizures: A Prospective Observational Study from Egypt

Author(s)

Rateb Abd Almonaem Eman | Shaheen Dabour Ahmed | Ahmed Elawady Mona | Mohamed Abdel Haie Omima | Issue Writer Certificate

Keywords

Infants

Neonate

Preterm

Outcome

Seizure

Abstract

Background: Neonatal Seizures are the most prevalent neurological disorders. In Egypt, the characteristics and neurodevelopmental Outcomes of neonatal Seizures have not been sufficiently explored. Methods: The present study was conducted on 120 full-term and Preterm newborns from October 2016 and October 2020. The adverse Outcomes of cerebral palsy, mortality, developmental delay, and/or epilepsy have been considered. The associations between adverse Outcomes and 13 variables were analyzed. Results: Hypoxic-ischemic encephalopathy (HIE) (34. 2%) was the most common etiology for neonatal Seizures, followed by intracranial hemorrhage (25. 8%). The predominant Seizure type was subtle (57. 5%), preceded by clonic Seizure (16. 7%). Moreover, 72 Neonates had a normal Outcome, 14 (60%) cases had minor functional disabilities, and 27 (22. 5%) newborns survived with one or more neurodevelopmental abnormalities (6 cases had cerebral palsy, and 21 newborns had global developmental delay), with a 17. 5 % mortality rate. Based on the univariate analysis, 10 variables were associated with an unfavorable Outcome; nonetheless, only three variables, namely metabolic acidosis, abnormal cranial ultrasonography findings, and the presence of congenital heart disease, were independent predictors as illustrated by multivariate logistics. Conclusion: As evidenced by the obtained results, HIE and intracranial hemorrhage were the most common causes of neonatal Seizures. Perinatal insult, prematurity, Seizure onset <24 hours, low Apgar score at 1 min, myoclonic or mixed Seizure, the efficacy of the anticonvulsant therapy, abnormal cranial U/S, metabolic acidosis, abnormal electroencephalography (EEG) pattern, and the presence of congenital heart disease were the most reliable predictors of adverse Outcome.

Cites

No record.

References

No record.

Cite

APA: Copy

Rateb Abd Almonaem, Eman, Shaheen Dabour, Ahmed, Ahmed Elawady, Mona, & Mohamed Abdel Haie, Omima. (2022). Clinco-etiological Profile and Predictors of Outcome of Neonatal Seizures: A Prospective Observational Study from Egypt. IRANIAN JOURNAL OF NEONATOLOGY, 13(2), 22-31. SID. https://sid.ir/paper/991035/en

Vancouver: Copy

Rateb Abd Almonaem Eman, Shaheen Dabour Ahmed, Ahmed Elawady Mona, Mohamed Abdel Haie Omima. Clinco-etiological Profile and Predictors of Outcome of Neonatal Seizures: A Prospective Observational Study from Egypt. IRANIAN JOURNAL OF NEONATOLOGY[Internet]. 2022;13(2):22-31. Available from: https://sid.ir/paper/991035/en

IEEE: Copy

Eman Rateb Abd Almonaem, Ahmed Shaheen Dabour, Mona Ahmed Elawady, and Omima Mohamed Abdel Haie, “Clinco-etiological Profile and Predictors of Outcome of Neonatal Seizures: A Prospective Observational Study from Egypt,” IRANIAN JOURNAL OF NEONATOLOGY, vol. 13, no. 2, pp. 22–31, 2022, [Online]. Available: https://sid.ir/paper/991035/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops