FLUNIXIN, KNOWN AS 2 [[2' -METHYL-3' - (TRIFLUOROMETHYL) PHENYL] AMINO] -3-PYRIDINE CARBOXYLIC ACID, IS A NON-STEROIDAL ANTI-INFLAMMATORY DRUG (NSAID), ANALGESIC, AND ANTIPYRETIC USED IN VETERINARY MEDICINE. IT IS OFTEN FORMULATED AS THE MEGLUMINE SALT. THE ANALGESIC ACTIVITY OF N-METHYL- D -GLUCAMINE SALT OF FLUNIXIN (FLUNIXIN MEGLUMINE) IS COMPARABLE TO THAT OBSERVED BY POWERFUL NARCOTIC ANALGESICS SUCH AS MORPHINE, MEPERIDINE HYDROCHLORIDE, AND PENTAZOCINE. HOWEVER, THE UNDESIRABLE SIDE EFFECTS ARE LESS COMPARED TO THE ABOVE MENTIONED NARCOTICS ANALGESICS AND DRUG DEPENDENCE LIABILITY DOES NOT OCCUR. A PART FROM ITS PARENTERAL ANALGESIC ACTIVITIES, FLUNIXIN MEGLUMINE ALSO POSSESSES ANTI-INFLAMMATORY ATTRIBUTES. THE PRESENT WORK INCORPORATES ENVIRONMENTALLY FRIENDLY REACTION CONDITIONS WITH ASSOCIATED BENEFITS LIKE EXCELLENT YIELD, STRAIGHT FORWARD WORK UP, AND USE OF COPPER POWDER AS A CHEAP, READILY AVAILABLE, EFFICIENT AND SAFE CATALYST, WHICH ARE IMPORTANT FACTORS IN THE PHARMACEUTICAL INDUSTRY.