In this research the 50/50 cotton/polyester fabric is treated with NaOH 24% w/w in 60, 90°C for 2,5, 10,90 min and some of the physical properties of the treated fabric samples including weight loss, regain, water drop absorbed, strength, elongation pilling whiteness and dye absorbed evaluated. The effect of sodium hydrosulphite as a reducing agent for absorption of oxygen in the processing media was studied. The results show that alkali treatment in 60°C for 10-20 min with NaOH 24% can hydrolyze the polyester fiber surface and also remove the impurities from the cotton fiber. This treatment may improve some of the fabric properties, for example increase in moisture regain, dye ability and decrease the water drop absorbed and pilling by the fabric.