Pars Journal of Medical Sciences
Year:2012 | Volume:10 | Issue:1|Papers Count:11

Introduction: Oxidative damage is one of the major factors that lead to cell damage, organ dysfunction and mortality in sepsis. Thus, an attractive candidate for pharmacologic treatment of the septic syndrome is deferoxamine (DFX), an antioxidant iron chelator used for the removal of iron and a potential free radical scavenger. In this study, the impact of DFX administration on the survival of septic animals was evaluated.Material and Methods: Sepsis was induced in 20 rats, using the Cecal Ligation and Puncture method (CLP) and 10 rats randomly received subcutaneous DFX (total dose: 40mg/kg) twice and the other 10 rats received placebo (normal saline). All the rats had equal health status, environment and nutrition. The time of the death of the rats was recorded.Results: Deferoxamine increased the survival period in rats and the difference was statistically significant.Conclusion: Treatment with DFX significantly increases the survival of septic rats.

Introduction: Depression and low self-esteem are the most important psychological disorders common among adolescents. But few studies have investigated the association between parental bonding patterns and depression and low self esteem in adolescents. The aim of this study was to detect the effects of parental bonding on depression and self esteem during adolescence in Bushehr in 2010.Material and Methods: In this cross-sectional study, a total of 482 adolescents (246 females and 236 males) in the first grade at 8 high schools of Bushehr were selected according to cluster random sampling. A series of valid and reliable questionnaire by each subject including the Beck Depression Inventory, Cooper Smith Self esteem Inventory and Parental Bonding Inventory (PBI) were completed. Descriptive statistics and independent t-test were used for analysis of the data in SPSS, version 11.5.Results: Parental care was more associated with depression and low self esteem in both male and female adolescents than parental protection. An interactive combination of low care and high protection (affectionless control) revealed a significant relationship with depression and low self esteem in female adolescents.Conclusion: The results showed that a combination of low care and over-protection increases the risk of depression and low self-esteem in female adolescents. Optimum parental behavior is characterized by the behavior through which adolescents get a feeling of freedom, love and protection.

v Introduction: Pseudomonas aeruginosa is a key opportunistic pathogen causing severe acute and chronic nosocomial infections in immunocompromised or catheterized patients. It is prevalent in burn wound infections and is generally multi-drug resistant. This study evaluated antimicrobial activity of ZnO nanoparticles, catechin and EDTA on the most common pathogen bacteria, Pseudomonas aeroginusa, by standard microdilution test depending on NCCLS.Material and Methods: Zinc acetate dehydrate and ethilen glycol (EG) were dissolved in 50 ml distilled water with a ratio of 10/1 (Zn/EG). The solution was heated at 80oC until a little gel of zinc acetate was obtained. Then, the gel was dried in the oven for 12h. The dried gel was calcinated at 300oC for 24h. The size and type of these nanoparticles were characterized by scanning electron microscopy (SEM) and X-Ray-: Diffraction (XRD). Pseudomonas aeroginusa strain (ATCC 27853) were cultured on nutrient agar medium (NA) for 24h at 37oC. The microbial suspension (1´106 cells/ml) was prepared. Minimum Inhibitory Concentration (MIC) test for ZnO, EDTA and Catechin were evaluated by microdilution test.Results: Evaluation of morphology and measurement of the size of the ZnO showed that nanoparticles were spherical with a diameter of 30-90 nm. MIC of ZnO, EDTA and Catechin on pseudomonas aeroginusa was 0.0003, 24.92 and 7.24 mg/ml, respectively.Conclusion: In this study, ZnO nanoparticles were synthesized using the chemical method. It was revealed that it has an optimal antimicrobial activity in low concentration as compared with Catechin and EDTA. It is recommended that catechin and ZnO nanoparticles are good candidates for eliminating some contaminations including Pseudomonas aeroginusa in medical industrial.

Introduction: Iran is one of the endemic countries of brucellosis with a prevalence of about 225 in 1000000 population. In this study, there was an attempt to evaluate the demographic characteristics and wright test titers in treated patients previously diagnosed with brucellosis.Material and Methods: In this descriptive cross-sectional study, 168 patients under treatment for brucellosis were evaluated during the years 2005 and 2008.Results: The mean age of the studied patients was 28.51±17.07 years and most of them were in 10-29 year old age group. 68.5% of the patients were male and 31.5% female. Most of the patients (60.1%) were shepherds; and their wright titer was 1/320 in 33.1% of the cases.Conclusion: Shepherds and those with 10–29 years of age are the high risk groups for brucellosis, so more attention should be paid in them. Males are more at risk than females. It is recommended that the serum of the patients be diluted up to 1/320 in standard tube agglutination test.

Introduction: Visfatin is an adipocytokine secreted from adipose tissue and can lead to the occurrence of diabetes. Omega-3 can decrease lipid profile and prevent insulin resistance. In the present study, the effect of Omega-3 on the serum visfatin concentration was compared with placebo.Material and Methods: A total of 71 women with type II diabetes were randomly assigned to a group that administered Omega-3 capsules or control group. First, the study subjects filled in a questionnaire including age, height, weight, waist circumference, and hip circumference. In addition, blood samples were taken to do the blood tests. In the second step, the intervention was done for 8 weeks and then data on the aforementioned variables were collected. In the blood samples visfatin and lipid profiles (LDL: low density lipoprotein, HDL: high density lipoprotein, TG: triglyceride and cholesterol), glucose, and HbA1c were measured.Results: There was no significant difference in serum visfatin level between groups before the intervention (p=0.14). However, after the intervention, the mean serum visfatin level in the Omega-3 group was significantly (P<0.001) higher. In addition, the mean differences before and after the serum visfatin level showed a significant difference in both groups (P<0.001).Conclusion: The use of omega-3 can increase visfatin level and also improve the effect of insulin in patients with type 2 diabetes.  According to the similar effects of insulin and visfatin, the use of Omega-3 by diabetic patients is recommended. Also, further studies are recommended to be conducted on his subject to confirm the results of this study.

Introduction: The aim of this study was to examine the effect of Vibration, PNF (Proprioceptive Neuromuscular Facilitation) and mixture stretching method on flexibility of the hamstring muscles in non-athlete male students.Material and Methods: In this study, 30 students were selected through goal oriented method and then divided into 3 groups: vibration (N=10), PNF (N=10), and mixture (N=10). Firstly, the flexibility of the hamstring muscles was measured by the “passive leg straight test”. Then, the 3 groups were trained for 4 weeks. After that, passive leg straight test was performed in the three groups.Results: The results indicated that the flexibility in all three groups significantly increased after training protocol (p=0.001). Although in the hamstring muscles there was no significant difference between the flexibility of the vibration and PNF groups (P>0.05), in the mixture group flexibility was significantly more than the other groups (p=0.000).Conclusion: Based on the results of this study, although the athletes achieve relatively favorable levels by vibration or PNF methods, the combination of these methods  contribute to the improvement  of  flexibility to the highest degree. Therefore, stretch training method is recommended in such sports as gymnastic, wrestling and dancing which need a high flexibility.

Introduction: One of the methods of breast cancer screening is its self-examination. This study reviews the effect of education about breast self-examination on women’s knowledge, attitude and practice.Material and Methods: This clinical trial was conducted on 100 (50 cases, 50 controls) women who referred to health centers in NourAbadMamasani. The participants in the experimental group were trained during 3 sessions. The data gathering tool was a questionnaire consisting of four parts: personal details, and questions on knowledge, attitude and practice. The collected data were analyzed in SPSS software using T-test, ANOVA, Regression and Chi square.Results: The results of the study showed that education increased the women's awareness, attitude and performance of breast self-examination. The mean scores of awareness, attitude and performance significantly increased after the educational intervention in the experimental group (p=.001) as compared to the control group (p=0.309, p=0.233, p=0.489).Conclusion: There is a need that health care centers provide some educational courses on prevention and treatment of breast cancer for women in the appropriate time.

Introduction: Children’s behavioral problems are a reflection of their parents’ psychological problems, especially mothers, and mental illness in one of the parents increases the likelihood of mental illness in the children. With regard to the negative interaction between parents and their children’s diseases, this study aimed to assess the relationship between the child’s behavioral problems and maternal mental health.Material and Methods: This study was conducted on 80 mothers with children with behavioral problems. They were referred to the pediatrics clinic of psychiatric ward in Golestan Hospital, Ahwaz city and selected through successive sampling. The instrument used contained a mental health questionnaire (SCL-90- R) and children's behavioral problems questionnaires (CBCL). Pearson correlation and regression analysis were used to analyze the data.Results: The results showed that there was a significantly positive relationship among all the children’s behavioral problems with all subscales of maternal mental health. There was a significant positive relationship between external behavioral problems of children with all subscales of maternal mental health. A significantly positive relationship was obtained between internal behavioral problems of children with all subscales of the mothers’ mental health except for the interpersonal sensitivity.Conclusion: With regard to the high correlation between children’s behavioral problems and maternal mental disorders, measures should be taken to reduce the effects of the mothers’ psychological problems on children.

Introduction: Despite the fact that cervical cancer is highly preventable, it still continues to occur, even among women who have access to cancer screening and treatment services. This study aimed to determine the effect of health education program based on Health Belief Model on the performance Pap smear test.Material and Methods: This random clinical trial was carried out on 120 women in Zarandieh. Data were collected using a valid and reliable questionnaire based on Health Belief Model which was completed by the participants. After the analysis of pre-test results, the educational program was designed and the experimental group participated in 3 educational sessions during one week. Two months after the intervention, a post-test was performed and analyzed using t-test, t-paired and x2.Results: Our findings indicated that mean scores of HBM Model constructs (self-efficacy, susceptibility, severity, benefit and barriers perceived) were significantly increased in the experimental group compared to the controls after the intervention. Also, performance of pap smear test increased significantly among the experimental group as compared to the controls after the intervention (P<0.01) (before intervention 30%, after intervention 53.9% in the experimental group).Conclusion: Health education programs are recommended to use the theories and models of changing of individuals' behavior in organization levels for to Help Plan Effective Programs as the uptake of cervical cancer screening (Pap smear).