To study the effect of iron foliar application on grain yield and its components in dryland wheat cultivars, a split plot experiment was carried out in 2012-2013 in Kermanshah, based on randomized complete blocks design with three repetitions. Treatments included time of foliar application with 3 levels (At tillering, heading and non - spray (control)) as main plots and cultivars in 4 levels (Sardari, Rijav, Biseton and Rashid) as subplot. Treats were number of spike per square meter, number of grain per spike, 1000-kernel weight, grain yield, and biological yield and harvest index. Results showed that time of application had significant effects on studied traits. Mean comparison showed that iron sprayed at tillering time had better effect and without spraying effect on all the characters had the least impact. Also it had significant effect on the studied characteristics as the highest number of spike (m2), number of grains per spike, 1000 kernel weight, grain yield, biological yield and harvest index, were with 456.3 spike, 13.1 grain, 35.6 g, 1943 kg/ha, 6885 kg/ha and 30.90 %, respectively belonged to the Rijav cultivar and the lowest amount of traits with a mean of 401.3 spike, 11.8 grain, 31.3 g, 1350 kg/ha, 6425 kg/ha and 21.01% belonged to Rashid. The spraying time × different cultivars on 1000 kernel weight and grain yield was significant in both iron foliar spray at tillering and heading Rijhav cultivar and Rashid had average of the highest and lowest respectively. According to the results, the best and most suitable time for iron spraying on dry land wheat is tillering stage of plant in Kermanshah and similar region.