Response of four varieties of sunflower to NaCl salinity at germination and early seedling growth was investigated. The experiment was conducted according to completely randomized design as factorial with two factors and four replications in Biotechnology Laboratory, Islamic Azad University- Karaj Branch. First factor including four varieties of sunflower: Azargol, Euroflor, Megasun, Hisun and second factor including salinity at five levels consisting of 0, -0.3, -0.5, -1, -1.5 MPa were used. Results revealed that the effect of variety for all the traits was significant. Effect of salinity on shoot fresh and dry weight, seedling dry weight was significant and for radicle fresh and dry weight, seedling fresh weight, germination percentage and germination rate, plumule and radicle lengths, radicle length/plumule length ratio and seed vigor was significant. Also, variety and salinity interaction on plumule dry weight, radicle fresh and dry weight was significant was significant and for plumule and seedling fresh weight, plumule and radicle lengths, radicle length/plumule length ratio and seed vigor was significant. All the traits were decreased when the salinity levels were increased. Mean comparison showed that the highest value of plumule and seedling dry weight, plumule, radicle and seedling fresh weight and radicle length was recorded for Hisun variety. Furthermore, maximum percentage and rate of germination and radicle length/plumule length ratio was observed for Eurofloe variety. In addition, Azargol variety had the highest value of radicle dry weight, radicle length and seed vigor.