Purpose: The aim of this study is to investigate the physical injuries of workplace among librarians of governmental universities of Isfahan based on Ergonomic principles.Methodology: The research method is descriptive survey by using questionnaire in 3 parts: demographic, Nordic, and library equipment and occupational conditions. Data analysis has been done by SPSS software, P coefficient of correlation and t-test.Findings: The amount of physical injuries at work according to different sections is Management/ 58%, Circulation/ 67%, Technical services/ %, and periodical/ 77%. The librarians who work in other sections have declared the mount of injuries 11/11%, and those who simultaneously work at several sections have 84% injuries. On the whole, the amount of physical injuries in 12 months is 41/42%, in 3 months is 29/95% and in a week is 21/74%. The amount of absence at work is 7/7% and the amount of going to doctor because of physical injuries is 6/2%.Conclusion: There is a significant relation between age, work experience, and doing exercise with physical injuries, but there isn’t a significant relation between gender, working hours, library equipment and occupational conditions with physical injuries.