The population is one of the most important categories and interdisciplinary concepts in which the changes have many socio-economic implications. Therefore, recognizing the factors affecting it and analyzing the trends of their changes is one of the most important issues for the purpose of proper and principled economic and social policy. In this regard, the present study addresses the socio-economic factors affecting population growth in Iran. For this purpose, using autoregressive distributed lag (ARDL) method, the components affecting population growth have been analyzed and analyzed. The variables of GDP, women's employment, total literacy rate and mortality of infants under one year were identified as explanatory variables that affect the total fertility rate in Iran as an independent variable. The results of this study indicate that the long-term fertility rate has a direct relation with the overall literacy rate, the rate of infant mortality and the employment of women, and has an inverse relationship with the growth rate of gross domestic product. In other words, women's employment is consistent with their cyclical behaviour, and national production has anticyclical behaiviour.