Watershed prioritization has an important role in natural resources and watershed management. This study deals with prioritization of 11 sub-watersheds of Asemangar watershed in Chaharmahal and Bakhtiari province using 13 morphometric parameters of linear, shape and topographic and a mixed multivariate linear model of new TOPSIS-Regression. A linear regression model was used to determine the morphometric parameter weights and prioritization was performed by TOPSIS decision Method. Results obtained from weighting analysis showed that mean bifurcation ratio, form ratio and ruggedness number have the most effect on erodibility and flooding with 0. 612, 0. 221, and 0. 212 scores, respectively. According to the results of prioritization, 4, 6 and 9 Sub-watersheds with the least distance to the positive optimum (0. 0062, 0. 051, and 0. 048, respectively) and maximum distance to negative optimum (0. 1734, 0. 1809, and 0. 1746, respectively) have the highest flooding intensity with maximum scores of 0. 7365, 0. 7777, and 0. 7841, respectively, that should be prioritized for action management and watershed management. In order to validate the results, special deposition and sediment delivery ratio (SDR) was calculated for each Subwatershed by PSIAC method using nine parameters including geology, climate, soil, water, topography, land cover, land use, surface erosion and river erosion. Validation of results indicate that the morphometric parameters and used model has a high performance of prioritization of watersheds prone to flooding and high erodibility; so that 4, 6 and 9 Sub-watersheds have the highest amount of Special deposition 97. 1, 80. 2, 70. 1 Ton/Hec/Year and sediment delivery ratio 57, 55, and 59 percentage, respectively. The results of this study can be used in watershed management.