This research entitled "The Role of Cognitive Mechanisms in Teachers' Ability Professional Development" has been conducted in years 1392-93. Sample space of this project includes all teachers of grade one secondary school in Ardebil (area 1 and 2), by means of Cochran formula, statistical samples were selected, and using simple random method and we selected 250 teachers, who were tested by the same method. In order to gather the data, we devised two kinds of questionnaires of "standard of Organizational Learning Mechanisms" and questionnaire of "ability of professional Development" and reliability of which ate 0.79 and 0.71 respectively. The gathered data were analyzed step by step using few statistical methods: "single sampled T", "Pirsons correlation coefficient" and "multiple regression analysis". The results indicate that the condition of Cognitive Mechanisms in grade one secondary schools in Ardebil town, has an average above normal. According to correlations based on the hypothesis of the research, it is indicated that there is a positive relation between Cognitive Mechanisms and ability of professional Development. According to the results of multiple regression analysis among different aspects of Cognitive Mechanisms, determining needs of growth & learning, utilizing learning in target situation and situation of learning, respectively which have influenced teachers' ability of professional Development. Therefore, by providing Cognitive Mechanisms infrastructure in the schools can be increased to improve the professional development of the teachers.