Investigation of Macrobenthic has been carried in Kor River, Fars Province, during one year study, from October 2007 to September 2008.Five study sites were selected in 250 Kilometers distance of the river, Benthic Macroinvertebrates were monthly collected and measuring. Benthic Macroinvertebrates were collected at each site using a Surber with 2400 cm² and 250µmesh net,this act with 3 repetition carried by method Davies 2001. A sample collect and fixed with formaldehyde %4, in laboratory has carried sort and enumeration. 32 Taxa Benthic Invertebrate were identified, overall average, members had dominated order Diptera and Ephemeroptera in stations 1and 2,Class of Gastropoda and Crustacea in station 3,Class Gastropoda and Diptera in stations 4,5. Benthic data were summarized according to Community Structure Metrics including EPT index, Chironomidae index,, TR, Shanoon index (H‘), EPT/CHIR and Biotic index(HFBI) estimated ANOVA one way of taxa Benthic Organisms and ANOVA 2 way with seasons and stations, The results analysis 0f variance and estimating of correlation showed significant difference in stations (P<0.05)The results showed none pollution up dorodzan dam and approximately to intense pollution in downstream of it in difference seasons and sites, The results showed that using Macrobenthic community is economy and quick method for good assessment of pollution specifically have strictly in seasons polluted.