Background and Objective: This research studies the environmental factors that may be influenced, considering the nature of the project and the way the various stages of utilization exert their influence, and the environmental resources that may be affected by the execution of the different stages of the project. Environmental influences are various changes caused by different activities in the physical, chemical, biological, cultural, economic, and social environments, with each project having different temporal and spatial effects. That is, the consequences and effects resulting from the different stages of construction, utilization, and post-utilization of projects are different. Material and Methodology: The environmental factors considered to study the environmental effects of the wastewater treatment plant in Yazd included the physico-chemical, biological, economic, and social environments. In each of the cases mentioned above, many different parameters are selected, depending on the features of the project, to serve as indices. These indices are used as criteria for comparison of options. In environmental studies of projects, the types of effects are differentiated and employed in environmental analyses. Findings: Considering the decision-making matrix, which included 10 options, and the results obtained from the ENTROPY method, the experts selected the main indices that were the criteria of the project. Index number 4 (water quality), index number 1 (soil quality), and index number 7 (sanitation and safety), with relative importance weights of 0. 192, 0. 179, and 0. 152, were ranked first to third, respectively. Discussion and Conclusion: It is very necessary to control, monitor and supervise the operation and maintenance issues of a sewage treatment plant in order to produce a standard quality effluent and increase it’, s efficiency during the operation.