The research purpose is to investigate the effectiveness of Quran's verses on the mental health of anxious and depressed women. Therefore, 60 women were randomly selected and assigned into control and experimental groups. The participants were required to fill in the General Health Questionnaire (GHQ), Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI). The research data were assessed be measuring mean, standard deviation, t-test and One-Way Analysis of Variances (ANOVA). Results indicated that the general health significantly increased in the experimental group, compared to the control group and the psychopathological symptoms decreased due to the use of Quran's verses. Moreover, listening to Quoran verses decreased the anxiety symptoms, whereas, it had no significant effects on depression symptoms.