nowadays, the sustainable development has become an ideal and great challenge. The universities are obligated to realize this ideal in higher education, and undoubtedly, the role of universities in sustainable development is undeniable. In the meantime, the appearance of entrepreneurial university is a response to increasingly importance of knowledge in the national and regional innovation system and new understanding of university; i. e. the institution which is counted as a factor for development, knowledge and technology transfer, and the source of creative inventions, and is good and thrifty economically. Therefore, present research is conducted to explain and investigate the entrepreneurial university model toward achievement of sustainable development in Mazandaran universities. This research, in terms of purpose, is an applied research, and in terms of data gathering, is a descriptive research. First, by means of literature review and interview with experts, the primiarly questionnaire is designed and the principal indices of entrepreneurial university model are extracted. Then, the FDEMATEL is used to explore the causal relations between variables, and finally, the (FDISM) is used to design the structural model. Results showed, among explored indices, five variables play a causal role and five variables play an effectual role. Results of fuzzy weighting technique showed, among explored indices, the indices of vision, mission, and strategy in university possess the most weight and importance. Also, FDISM approach showed the variables have been categorized into seven levels, and the variables of vision, mission, and strategy in university, leadership in university, and organizational structure and design in university are more influential as infrastructural factors.