Journal of Sabzevar University of Medical Sciences
Year:2021 | Volume:28 | Issue:3|Papers Count:18

Introduction: Due to the increasing rate of Covid-19 disease, experiencing a high level of fear and anxiety is predictable. In this regard, this study aimed to investigate the relationship between fear of Covid-19 and health anxiety through the mediating roles of behavioral activation and inhibition system. Materials and Methods: The design of the present study was descriptive-correlation and path analysis. The statistical population of this study included Iranian adults from which 605 people were selected by convenient sampling method. Data were collected using the Health Anxiety Inventory (HAI-18), Fear of COVID-19 Scale (FCV-19S) and Behavioral Activation and Inhibition Systems Scale (BAS / BIS Scale). Data analysis was performed using Pearson correlation, multiple regression and path analysis. Results: The findings showed that there is a significant correlation (P <0. 01) between fear of COVID 19, Behavioral inhibition system and reward responsiveness subscale of behavioral activation system with health anxiety. In addition, the Bootstrap results indicate that the mediating roles of the behavioral inhibition system (0. 001) and the reward responsiveness subscale of the behavioral activation system (0. 006) is significant. Conclusion: Based on the findings of this study, fear of COVID 19 can predict and affect health anxiety through interaction with behavioral inhibition system and reward responsiveness subscale of the behavioral activation system. Therefore, interventions based on the introduction of prevention programs concerning Covid-19 to reduce the fear and anxiety of people about getting it, have positive results and can be considered as prevention programs to help people overcome experienced health anxiety.

Introduction: Health literacy can be understood as the ability to read, understand, and act on the basis of health and self-care recommendations, to follow a healthy lifestyle to prevent diseases. Health literacy is considered as one of the important components of self-care. The aim of this study was the relationship between of health literacy on self-care and preventive behaviors. Materials and Methods: This descriptive-analytical study was performed on 359 people living in the margin of Sabzevar city. Data were collected by questionnaires. Collected data was analyzed using SPSS16 software (descriptive and analytical statistics) using Correlation Coefficients and T-test and ANOVA. Results: Most of the subjects had enough health literacy with 54. 9%, and only 7. 5% had inadequate health literacy level. In addition, 37. 6% of people had a borderline health literacy level. The mean of health literacy in men was 84. 49 ± 13. 66 and the mean of health literacy in women was 86. 67 ± 14. 02, and also there was no significant difference in health literacy between the two sexes. Of the 359 people surveyed, the highest scores of 206 (57. 4%) were moderate and the remaining 153 (42. 6%) were poor and none of the subjects scored Have not gotten strong. here was no significant relationship between total health literacy and self-care, but there was a significant relationship between total health literacy with dimensions of self-care including mobility / fatigue, happiness, social functioning and pain. Also, self-care alone had a meaningful relationship with dimensions of health literacy only with the skill dimension of activity, and with other aspects of it there was no meaningful relationship. Conclusion: On the other hand, due to attention It was suggested that only half of the people had adequate health literacy, and none of them had proper self-care status. Therefore, effective measures are needed to increase the level of health literacy and consequently self-care promotion.

Introduction: One of the hospital’ s evaluation methods is the use of national accreditation standards, which its consideration causes enhancement in both patient safety and quality of services. It is essential for managers and personals whom involved in accreditation to have a positive knowledge and attitude. This study was done to assess Nurses Knowledge, Attitude, and Comment on Hospital Accreditation and its Impact on Patient Care Quality in Imam Khomeini Hospital in Sarab. Materials and Methods: This research is a descriptive cross sectional study which has been done. In order to collect the information, we used the corrected questionnaire of azami et al. Imam Khomeini hospital nurses 126 mirage with a minimum of one year of work experience to the classified random sampling method in this study. Data analysis were done using SPSS software. Results: The average knowledge score was 36 points (18. 22), attitude was 60 points (32. 76), comment was 50 points (25. 98) and nursing care was 5 points (2. 72). The average score for knowledge, attitude and comment showed that a modest positive about attitude, knowledge, and positive comment was seen. Conclusion: Enhancement of knowledge and creation of a positive perspective about accreditation may reduce anxiety and stress caused by the accreditation and the quality of nurses care of the patient is also can increase.

Introduction: Improving the quality of patient care is one of the challenges of the health care delivery system, and the performance of nurses as the largest health care professional group has a significant impact in this regard. The aim of this study was to determine the quality of patient care from the viewpoint of nurses and patients at the Shohada center. Materials and Methods: This was a descriptive-analytic study in which 63 nurses who were admitted to the study were randomly selected. For each nurse, 3 patients were selected according to available data. Data was collected using standard questionnaire QUALIPAC was collected. The results were analyzed using SPSS version 24 and chi-square, and Pearson’ s correlation test. Results: The mean of quality of care in view of patients and nurses were respectively, psychosocial aspect 61. 66 ± 1. 46, 80. 28 ± 1. 66, in physical aspect 57. 93 ± 1. 43 and 76. 15 ± 1. 52 and in communitive aspect 57. 93 ± 1. 43 and 39. 19 ± 0. 83. There was a significant statistical difference between patients and nurses views in three aspects (P=0. 001). Also, there was no significant relationship between the demographic characteristics of the nurses and patients (age, sex, clinical experience, place of residence, etc. ) with quality of care (P> 0. 005). . Conclusion: According to the findings of this study, it is suggested that using educational courses for nurses and nursing students, especially communication skills, using the system of encouragement and punishment, as well as continuous controlling and monitoring can be promoted the quality of patient care.

Introduction: Since removal of dyes causing cancer from colored wastewater before releasing into environment is very important therefore in this study the effective parameters in removal of dye AR 18 with a new organic adsorbent were investigated by combining the two methods (adsorbent) and chemical method (AOPS). Materials and Methods: Firstly, a rotary reactor was made up then for each experiment 100mL of sample was exposed to UV ray, H2O2 and extracted carbon from carrot meal. In this study low power UV lamps and in a reactor with capacity of 1. 5L were used. Properties of adsorbent were studied and illustrated via TEM, SEM, XRD. Effects of parameters such as pH, UV radiation contact time, concentration of dye and concentration of adsorbent were examined and optimum points of each parameter obtained. Inlet and outlet of dye concentration was measured by spectrophotometer. adsorption Equilibrium and adsorption kinetics with maximum adsorption capacity were measured accordingly. Results: Physical properties of active magnetite carbon showed that Fe3O4 nanoparticles had average size of 22-90 nm with the BET of 480 m2/g. acid red dye 18 was removed with 99 % efficiency where adsorbent concentration: 1/5gr. L, dye concentration: 25 ppm, pH: 4 and contact time: 80 min. adsorption capacity: 126/98 mg/g and adsorption kinetics is in line with Pseudo-second-order model (R2=0/99, AR 18). Conclusion: Results of this study showed that using extracted carbon from carrot meal together with UV radiation as a low cost adsorbent, Eco-friendly is significantly effective in dye removal via.

Introduction: Polycystic ovary syndrome (PCOS)is the most common endocrine disorder in women of childbearing age. There are many challenges regarding the quality of oocytes in these individuals. Therefore, this review study aimed to investigate the consequences and challenges associated with in vitro fertilization in women with polycystic ovary syndrome. Materials and Methods: For related studies, the Persian SID and Magiran databases and Pubmed, Scopus, Elsevier, Weily online library, Sciences Web of Science databases and Google Scholar search engine were used for the period 1990– 2019. To obtain all articles in Persian and English, the keywords of Polycystic ovarian syndrome, in vitro fertilization, Polycystic ovarian morphology, IVF outcome, Oocyte donation, Oocyte competence, Pregnancy, and their Persian equivalent are used separately or as possible combinations. From 450 articles, 17 were eligible and selected for this study. Results: The results of various studies suggesting major challenges in this group of women including gonadotropins need and hormone-related changes, ovarian hyperstimulation syndrome (OHSS), clinical pregnancy rates, pregnancy outcomes and the risk of miscarriage, the quality of oocytes in women with polycystic ovary syndrome undergoing in vitro fertilization and the issue of egg donation in this group of women. However, fetal loss, clinical pregnancy and live birth rates are no different from other women. Conclusion: Due to concerns about pregnancy in women with PCOS, closer monitoring of these pregnancies is important, it also appears that the presence of PCOS in donors does not affect the rate of pregnancy or implantation and the number of embryos transferred in ovarian donation programs. As a result, women with PCOS should not be excluded from egg donation programs.

Introduction: Sjogren-Larsson Syndrome (SLS) is a recurrent autosomal recessive disorder characterized by three main symptoms including ichthyosis, mental retardation, dysplasia, or spastic tetraplegia. However, other symptoms such as cognitive deficits, delayed speech and seizures were frequently observed. Because of these overlap symptoms, these syndromes are categorized as unknown and rare disease. High-through put technologies such as whole exome sequencing (WES) solved many of these unknown diseases. In this study, we used WES and introduced a family with SLS from Sabzevar – Khorasane Razavi-Iran. Materials and Methods: Using WES, we sequenced all exons and then analyzed the annotation file. We segregated variant in other family members to confirm the candidate gene using PCR and Sanger sequencing. Results: Our data showed that mutation in ALDH3A2 with c. 943C>T pathogenic variant causes SLS syndrome in this family. Conclusion: The advent of WES improve the ability of diagnosis in a huge number of syndromes with overlap symptoms. Nonetheless, most of syndromes do not have a specific treatment and recognizing the cause of syndromes help to families to screen during pregnancies.

Introduction: Ethephon is a hormone used to accelerate the plant growth regulator processing. Mostly, after entering to the tissues, causing disturbance in reproductive system and subsequently decreased sperm fertility potential. The aim of this study was to investigate the effect of ethephon on embryonic morphological parameters and CatSper 2 protein localization in sperm. Materials and Methods: In this experimental study, 78 males and females (NMRI Strain) mice randomly divided into experimental and control groups. The experimental groups received ethephon at doses of 120, 240 and 480 mg/kg as well as the positive-control group received neostigmine (0. 1 mg/kg). After treatment, the animals were sacrificed and euthanized. Sperm samples were collected from cauda epididymis for qRT-PCR and immunohistochemically evaluation and stored at-70 ° C until examination. Results: The results of morphological parameters showed that hatching percentage, viability, number and length of fetuses in experimental groups were lower than control group. There was also a decrease in the expression of CatSper 2 gene in the experimental groups compared to the control group. Sperm immunohistochemical results indicated that there was no localization for the CatSper 2 protein in the experimental groups versus the ones (p<0. 05). Conclusion: Ethephon by producing free radicals causes decreased embryonic morphological features. It also impairs fertility and reproduction by decreasing the expression of CatSper 2 gene and lack of protein localization in sperm.

Introduction: Phenytoin ointment is a usual medicine for wound healing. Aloe vera gel promotes wound healing by directly stimulating the activity of macrophages and fibroblasts that increase both collagen and proteoglycan synthesis, thereby promoting tissue repair. The aim of this study was to evaluate the effects of phenytoin ointment1%, aloe vera gel, royal jelly and honey on skin wound healing in rabbit animal model. Materials and Methods: 5 rabbits with 50 skin wounds were used in this study. Phenytoin ointment1%, aloe vera gel, royal jelly and honey were used in four wounds and another was considered as an untreated control. Macroscopic study was performed on days 4, 8, 12, 16 and 20 after wounding and histopathologic study was done on the days 10 and 21 from the wounds. Results: On the 8th and 12th days in the Aloe vera gel, royal jelly and honey groups, the area of the wound had a significant difference (P<0. 05) than group1 (phenytoin), indicating a faster reduction of the wound surface than the phenytoin group. On the 16th day after surgery, the ulcer surface of the honey group was completely closed and on day 20 all the wounds were fully restored in all groups. Also, histopathologic studies on 10 and 21 days showed no significant difference between the studied groups and all wounds were completely restored on day 20. Conclusion: Finally, the results of this Study showed that phenytoin 1% ointment, aloe vera gel, royal jelly and honey, all had a good effect on wound healing.

Introduction: The production of high wastewater is one of the problems of recycling paper industry, it is essential to provide appropriate economic and environmental solutions for proper management and treatment. So in this research, the purpose was of optimization the treatment of wastewater products from the paper recycling industry with using magnesium chloride in combination with cationic and anionic polyacrylamides. Materials and Methods: This was an applied research which was done on a laboratory scale. The different pH (4-12) values at a fixed concentration of magnesium chloride to determine the optimum pH was investigated. Then optimization of concentration for magnesium chloride (200-700 mg/L) and polyacrylamides (0. 5-3 mg/L) was performed. At each stage of optimization, the parameters of TSS and COD were measured. Pearson correlation coefficient was used for analysis of data and significance level was 0. 05. Results: According to the results, pH=10 as optimal pH and concentrations of 500 and 1. 5 mg / L were selected as optimal concentrations for magnesium chloride and cationic polyacrylamide, respectively. Under optimal conditions, the efficiency of removing TSS and COD was 96% and 83. 07%, respectively. Conclusion: The results showed that magnesium chloride combined with cationic polyacrylamide, can be used as an appropriate option for wastewater treatment of paper recycling industries.

Introduction: Appendicitis is one of the medical emergencies and one of the most common causes of acute and severe abdominal pain worldwide. If appendicitis is not treated in time, the inflamed tissue of the appendix ruptures, followed by peritonitis and shock. Because the process of appendicitis is an inflammatory process, the acute phase proteins and whole blood bilirubin appear to produce high levels in the serum under these conditions. Materials and Methods: The present study is a descriptive cross-sectional study that was conducted in 2014-2015 with the participation of 208 patients over 15 years of age with symptoms of acute appendicitis referred to the emergency department of Dr. Beheshti in Sabzevar. In order to check the level of total bilirubin, 2 cc blood samples were taken from the patients before injecting any antibiotics and performing surgery. After the operation, macroscopic findings such as appendix size, perforation or absence during surgery and pathological findings were collected by the researcher. Results: The results showed that there was a significant relationship between total bilirubin and perforation in terms of macroscopy and pathology (p< 0. 001). Conclusion: There is a significant relationship between whole blood bilirubin level before surgery and acute appendicitis perforation and can be used along with clinical signs as a laboratory criterion to predict perforation.

Introduction: Sports injuries among physical education students are prevalent and various factors, including management factors, affect them. Materials and Methods: In this cross-sectional study, by using the systematic design of the data based theory required information was collected from 12 physical education teachers through targeted interviews. The interviews were then coded and a theoretical model of the research were developed. Finally, in order to evaluate the accuracy of theoretical model a questionnaire was designed and completed by 330 physical education students and the effect coefficients of different parts of the model were investigated by modeling structural equations in PLS software environment. Results: The results of the analysis of qualitative data obtained from the interview led to the presentation of the model of prevention of sports injuries of physical education students based on managerial factors with 13 categories and 38 concepts in the form of 6 dimensions including causal factors, the main phenomenon, strategy, background characteristics, intervening conditions and outcomes. General test of structural equation modeling was performed using the Goodness of Fit Test and was confirmed(GOF = 0. 74). The statistical value of T for the effect of each of causal factors, background characteristics, intervening conditions was higher than (1. 96), so their effect was confirmed. Conclusion: Thus, by modifying the approach of student admission, educational programming and securing places along with teaching and informing, we will be able to significantly reduce the incidence of sports injuries in physical education students.

Introduction: Nursing record is the most important communication method between clinical caregivers including nurses & midwives. Studies have shown that recording errors is considerable among Iranian nurses. Insufficient education in the field of recording is of a significant. Cause. So, recording education can improve clinical caregivers' performance in this field. The aim of this study was comparison the effect of nursing record educatoin based on critical thinking with rutine method. Materials and Methods: This quasi-experimental study of two groups before and after was carried out on 70 nursing and midwifery personnel. at first, sampling method was simple randomization. Then, samples randomly assigned to the experiment and control groups. The recording skills of nurses and midwives assessed before and after using the standard checklist of the Ministry of Health and Treatment in three different times. Data were analyzed using SPSS software version 20 and t-test, and linear regression test. Results: Comparison the mean scores of nurses' performance in two groups of routine and critical thinking education did not show significant difference before education. (P>0/05). There was significant difference between the mean score of nurses' performance in two groups before and after education (P<0. 001). But, the mean scores was higher in critical thinking group. There was no significant differences between work experience, field, and grade, with recording skills (P>0/05). Conclusion: Nursing record educatoin based on critical thinking is more effective than intraward routine educations.

Introduction: The risk of starvation and the increasing number of hungry people around the world has increased due to the world's population growth and lack of food and supplies. Climate change, in addition to global population growth, has affected food shortages. As a result, food security is at risk. Therefore, challenges has been paid to Genetically Modified Crops and Genetically Modified Food. The aim of this study was to investigate the health, legal and ethical challenges of transgenic food consumers. Materials and Methods: This paper is a narrative review; the search was done on articles and books in Persian and English, published and indexed in PubMed ScienceDirect, Google Scholar, SID, IranMedex, and Magiran databases. This search was carried out individually and in combination, with no time limit in published and indexed articles and books until the end of 2021, and after retrieval, they were reviewed and analyzed. Results: In this narrative review study, the health, ethical and legal challenges of GM food to consumer rights were examined to show how a balance can be struck between the right to food and the right to health and food security. Conclusion: The Non-Maleficent Ethical Rule requires that governments closely monitor producers of GM crops and foods in order to ensure food security and prevent producers from abusing their rights. Therefore, the production of GM crops and foods should not cause harm to the consumer and the environment around him. In addition, the consumer must be aware of the presence of GM foods in order to exercise his or her choice right.

Introduction: Considering the harmful and irreparable effects of addiction to prevent serious harm to students, it seems that measures should be taken in this regard. The aim of this study was to compare the effectiveness of group schema therapy and planned behavior training on student addiction of teachers at Farhangian University of Mashhad. Materials and Methods: The design of the present study is quasi-experimental in three groups with pre-test and post-test. The study population was all student teachers in the campuses of Khorasan Razavi province in the academic year of 2019-2020. Forty-five student-teachers were randomly assigned to three groups: schema therapy (n=15), planned behavior training (n=15), and control (n=15). The intervention groups underwent 11 sessions of 60-minute schema therapy and 8 sessions of 90-minute planned behavior training, respectively, and the control group did not receive treatment. Data by scale Goldsmith Addiction (2006) It was collected during three stages and analyzed by repeated measures analysis of variance. Results: The research findings showed that group schema therapy and planned behavior training are effective in reducing student-teacher addiction. This effect after one month follow-up in both groups was durable (P <0. 01). There was also a significant difference between the two interventions (P<0. 01). Conclusion: Both schema therapy and planned behavior training can be effective in preventing youth addiction.

Introduction: Leishmaniasis is a disease in tropical regions, that includes a wide range of clinical protests, from skin lesions to fatal visceral infections. A2 gene is accounted as one of the most reliable genetic factors cause visceral form. This gene is a single copy without functional expression in the species causing skin form of the disease such as L. major and L. tropica. The aim of our study is to evaluate A2 gene sequence in the strains that cause skin form of disease and compare it with other exception strains of the Leishmania tropica strains in Iran. Materials and Methods: Leishmania species were detected using ITS1 and ITS2. The parasites were injected into BALB/c mice and monitored of footpad inflammation in BALB/c mice. after a certain period of time the mice were killed and their visceral organs were examined for the presence of parasites. Finally, A2 gene sequence analyzed. Results: A2 gene in a strain causing visceral form was different to a gel electrophoresis pattern of skin form causing strains. Also, the gel electrophoresis pattern of A2 gene in strains causing skin form was different to previous reports of cutaneous leishmaniasis. Conclusion: The results of this recent experiment showed that the gel electrophoresis pattern of A2 gene in especial strains causing viseral form was similar to previous reports of visceral leishmaniasis. It seems that this gene may play an important role in the visceral ability of specific strains of Leishmania tropica.

Introduction: Obesity is a metabolic disorder that can be controlled and prevented by increasing energy expenditure and stimulating factors related to the browning of white adipose tissue. The aim of this study was to investigate the effect of high-intensity resistance training on Irisin and Fibroblast growth factor 21 (FGF21) levels in overweight men. Materials and Methods: In this semi-experimental study, 20 overweight men (mean 36. 56± 3. 33 years and body mass index 29. 41± 3. 02 kg/m2) were randomly selected. They were assigned in two groups of high-intensity resistance training and control. The program of the Resistance Group was conducted in a circular shape with an intensity of 85-80% of a maximum repetition, three sessions per week for eight weeks. 24 hours before and 48 hours after the training period, serum Irisin levels and FGF21 subjects were measured in the fasting state. Data analysis was performed by correlated t-test and ANCOVA at the significance level of P<0. 01. Results: Irisin and FGF21 Serum levels in the high-intensity resistance training group showed a significant increase compared to the control group (P<0. 01). Bodyweight, BMI, and body fat percentage in the high-intensity resistance training group showed a significant decrease compared to the control group, while a significant increase was observed in the control group (P<0. 01). Conclusion: It seems that high-intensity resistance training can be emphasized as an effective step in convert white adipose tissue to brown and improving the body composition of overweight and obese people.

Introduction: Multiple sclerosis is a progressive neurodegenerative disease. marital satisfaction is an important indicator in the favorable prognosis of treatment in progressive neuropsychological disorders. The aim of this study was to compare the effectiveness of two approaches of couple eclectic behavioral therapy and combined treatment of schema based on acceptance and commitment on marital satisfaction in women with multiple sclerosis. Materials and Methods: In a randomized pilot trial, During late 2019 and early 2020, 42 female patients with multiple sclerosis with their husbands were selected using purposive sampling method and using block randomization method in the form of two A treatment group and a control group were assigned. The two treatment groups underwent one of the eclectic and integrated behavioral couple therapy treatments based on acceptance and commitment for 10 sessions of 90 minutes once a week, and the control group was placed on a waiting list. Enrich Marital Satisfaction Questionnaire (1998) was completed by participants in three time periods: pre-test, post-test and follow-up. Data were analyzed using analysis of covariance and repeated measures. Results: Preliminary results showed that both treatments had a significant effect on patients' marital satisfaction index compared to the control group, which remained stable until the quarterly follow-up stage (all p's <0. 05). In addition, the secondary results showed that there was no significant difference between the effectiveness of the two treatments (p <0. 05). Conclusion: The findings of this study can be associated with clinical applications in planning the vision of therapeutic interventions in patients with neurodegenerative disorders.