Medical Journal of Mashhad University of Medical Sciences
Year:2015 | Volume:58 | Issue:7|Papers Count:12

Introduction: Diabetes Mellitus is the main cause of kidney failure. Identification of factors associated with kidney failure can help in fast diagnosis and on time prevention of this problem. The present study aims to compare the degree of blood hs-CRP, C Cystatin, and Ferritin in type II diabetic patients based on urine albumin level.Method: in this descriptive-analytic study which was a cross-sectional research, 90 patients including 30 people with normal urine albumin level, 30 subjects suffering micro-albuminuria, and 30 cases suffering macro-albuminuria were chosen from diabetic patients who had referred to diabetes clinic of Valiasr hospital affiliated to Birjand University of Medical Sciences. Sampling was done randomly and all participants had inclusion criterion. Tests of blood hs-CRP, C Cystatin, Ferritin, and serum glycosylated hemoglobin were performed for all participants. Data were analyzed using SPSS16 statistical software and statistical tests of one-way variance analysis, Tukey range follow up, Kreskas-Wallis, Mann Whitney U and multivariate regression analysis at significant level of p£0005.Results: Results showed that the average level of Ferritin was significantly higher in patients of macro-albuminuria compared to patients with normal urine albumin level and average level of Cystatin was significantly higher in patients of the group with normal urine albumin compared to the two other groups (P<0.05). But hs-CRP levels in patients with urine albumin levels were not significantly different. Average level of glycosylated hemoglobin was significantly higher in patients with macro-albuminuria compared to patients with normal urine albumin and micro-albuminuria.The results showed that Cystatin alone can explain about 7% of diabetic nephropathy.Conclusion: Measurement of serum level of C Cystatin can be used in diagnosis of initial stages of diabetic nephropathy in patients with type II diabetes.

Introduction: Regular consumption of green tea may influence energy metabolism, body weight and body fat content. The purpose of this study was to investigate the effect of eight weeks aerobic training and moderate and high doses ofgreen tea consumption on body composition and lipid profile in overweight and obese women.Materials & Methods: A total of 36 overweight and obese women selected and randomly divided into three groups, aerobic training with moderate doses of green tea (500 mg), aerobic training with high doses of green tea (750 mg), and placebo (starch). Both training groups performed aerobic training (3 sessions per week, each session 45 minutes) and consumed green tea for eight weeks. Placebo groups had no training during this period. Blood sample were taken in the fast state. Data were analyzed using one-way ANOVA and LSD post-hoc tests (a£0.05).Results: Overall eight weeks aerobic training combined with moderate and high doses of green tea supplementation significantly decreased weight, BMI, body fat percent age and increased VO2max, however, there were no significant differences between the two groups in these variables. Also, there were no significant differences in WHR, LDL-C, HDL-C, Tchol and TG, between the three groups.Conclusion: Overweight and obese women probably could modify body composition via aerobic training in combination with green tea supplementation. Also, it was suggested to use high doses of green tea with aerobic training on relation to lipid profile.

Introduction: Cardiovascular complications are the most common Cause of death in ESRD patients. Hypertension is one of the traditional risk factors of CVD. The Aim of this study was to investigate the association between Concentration of Na dialysate and blood pressure in chronic hemodialysis patients.Material & Methods: This cross sectional study was performed on 266 adult patients undergoing of hemodialysis at least for 3 months. Pre HD systolic BP and post HD systolic BP during 4 weeks were measured in relation to Na dialysate concentration. The other main factors affecting the post-dialysis blood pressure, such as Body Mass Index (BMI), pump speed, dialysis solution temperature, duration of dialysis and intradialysis weight gain (IDWG) were considered. Mean of DSBP (post HD sys BP - pre HD sys BP) in each patient in 12 sessions of HD was measured and statistically analyzed in relation to dialysate Na with SPSS 21. Backward multivariable linear regression analysis and Pearson correlation coefficients were used to evaluate the correlation between sodium gradient and DSBP.Results: Systolic blood pressure was significantly changed before and after dialysis in relation to dialysate Na (p<0.001). The analysis was stepwise multivariable linear regression. Those variables with significant values, such as dialysate Na concentration and blood flow rate (pump speed) remained in final step. The person’s correlations between ΔSBP with dialysate sodium and blood flow rate (pump speed) were statistically significant (p<0.01).Conclusion: We Found that changes in systolic blood pressure before and after dialysis significantly associated with dialysate sodium concentration.

Introduction: Nowadays Acinetobacter baumannii strains resistant to multi-drugs (MDR) are as one of the most problematic opportunistic pathogens, especially in the intensive care unit (ICU) in the world. This study aimed to characterize the antibiotic susceptibility pattern of Acinetobacter baumanii isolated from patients in intensive care unit (ICU) of Motahari hospital, Gonbad, Golestan.Material and method: The clinical samples isolated from hospitalized patients in ICU sent to the laboratory for detecting Acinetobacter baumannii by biochemical tests and confirmed by PCR and antibiotic susceptibility test performed and then the obtained data were analyzed by SPSS software and chi-square test.Results: According to the antibiotic susceptibility testing, from 50 Acinetobacter baumannii isolates of ICU, 64%, 24% and 12% of isolates were MDR, Non MDR and XDR respectively. The highest rate of antibiotic resistance was to Ceftriaxone, Ticarcilline and Erythromycin, also the minimum resistance was to Minocycline.Conclusion: Due to the fact that the rate of MDR was high in this study, the antibiotic susceptibility test is necessary before prescribing antibiotics and the correct use of antibiotics should be considered. Since it was found in our study that all strains insensitive to Imipenem were susceptible to Tobramycin and Minocycline, for treatment of infections caused by strains which are resistant to Imipenem, the combination of other antibiotics such as Tobramycin can be used.

Introduction: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-age women with insulin resistance and obesity of its properties. So, the aim of present research was studying the effect of 8 weeks of resistance training on ovary morphology, Glycemic control and body composition in the women with PCOS.Methodology: 18 women with polycystic ovary syndrome aged 18 to 30 years (BMI [1] ³25) were randomly divided in to Atotal of experimental groups (n=9) and control (n=9) groups. To evaluate the morphology of the ovaries as well as blood, samples after 12 hours of overnight fasting before exercise and 48 hours after the last training session are taken. Afterwards exercise group participated in an 8-weeks resistance training program.Results: The results showed that resistance exercise good effect in reducing fasting plasma glucose (P=0.014), insulin (P=0.001) and insulin resistance index (HOMA-IR) (P=0.001) and this practice is improvedthe right ovary volume (P=0.001) and left ovary volume (P=0.001). Also showed that 8 weeks of resistance training resulted in improved body composition indices including weight (P=0.001), WHR [2] (P=0.001), BMI (P=0.347) and body fat (P=0.010) in women with polycystic ovary syndrome.Conclusion: Resistance training had beneficial effect on the morphology of the ovaries and the glycemic index in women with polycystic ovarian syndrome, and can be used as a safe treatment and is recommended in these patients.

INTRUDOCTION: Obesity has been known as the most important risk factor for diabetes type 2 and different indexes of anthropometry such as waist circumference, hip circumference and body mass index (BMI), expressing the problems of obesity. The aim of this study was to investigate the relationship between these indexes and diabetes.Method and Materials: In this cross-sectional study conducted in 1389, 7000 people over 30 years old were screened for diabetes. Participants selected by convenient sampling from Samen health centre. The needed information were extracted from data files and put in SPSS software, then analyzed.Results: Over all 540 participants were diabetic, 4771 were at risk of diabetesand 1689 persons were healthy. There were significant relationship between waist circumference, hip circumference, waist/hip ratio, waist/height ratio, and BMI in three groups of diabetics, prediabetics and healthy people (p<0.001). We also found significant relationship between sex and three studied groups (p<0.001).Family history of diabetes, B.M.I, hip circumference, w.c/height and diastolic hypertension were predictors of fasting blood sugar with significant relationship (r2=0.06).Conclusion: Regarding to relations between anthropometric indexes and diabetes affecting, it goes without saying that in order to prevent obesity, teaching for improving life style, suitable nutrition, doing exercise, and mobility seems to be needed.

Introduction: Damages caused by sunlight on the eyes and skin without adequate coverage, especially in the head and neck during childhood and adolescence are likely to Cancer risk in adulthood increased. The aim of this study was comparing the booklet and animation programming methods in prevention of exposure to sun harmful effects among male students.Materials and methods: This semi-experimental study was conducted on 200 sixth grade male students that were randomly divided into two groups in several steps: booklet and animation programming. Information was collected by a multiple questionnaire that its validity and reliability were confirmed. At first pre intervention data were collected and then educational intervention in both groups conducted. A lecture along, showing a movie clip and educational match about the clip, were designed for the first group. For the second group, lecture along a Q& A session was employed, and then booklets were distributed among the students. After 2 months, data were collected again and analyzed by SPSS.16 using independent and paired T-test, chi-square. in this study 0.05 was considered as a Significanr levelResults: Means of differences scores for knowledge and behavior were in booklet group1.38 and 0.33 and in movie clip group6.33and1.52. The results indicated that, showing films and animations were more effective and motivative than the one with bookletConclusion: Considering the results, educational programs appropriate for students’ age, and preferably motivative and attractive educational methods should be organized for them.

Introduction: Varicose is a condition that mainly occurs in the lining of the veins in the bottom of calf. It causes high blood accumulation and swelling in the legs. The purpose of this study was to investigate the effects of aquatic exercise on pain severity and quality of life in women with varicose veins.Material and Method: Atotal of Forty non exercised females with mild varicose and an average age of 41±8.721 years, mean weight of 69.72±10.183 kilograms were selected as volunteers, and were divided into two groups: hydrotherapy group and control group. Hydrotherapy group performed 18 sessions of exercise training, three sessions per week and each session 60 minutes with an intensity of 50-60 percent maximum repetition for each person. The change of pain measured by scale of VAS and quality of life measured by means of the Short-Form Health Survey-36 (SF-36). Data were analyzed by paired and independent samples t-test at a significant levels of P<0.05.Result: The findings showed that in hydrotherapy group pain severity significantly decreased and quality of life significantly improved (P=0.000). While, in control group we just observed an improvement in quality of life (P=0.000). The inter-group differences in pain severity and quality of life were also significant (P=0.000).Conclusion: The results showed that aquatic exercise had a positive impact on reducing pain and improving quality of life of women with varicose veins.

Introduction: We reported on a case of Eosinophilic granulomatosis with polyangiitis (EGPA), formerly named Churg-Strauss syndrome (CSS) with colon ulceration, abdominal pain and heart failure With fatal progression of disease within 2 weeks.case presentation: A 21-year-old woman with a history of bronchial asthma and allergic rhinitis was admitted with severe abdominal pain, nausea and vomiting for two weeks before admission Laboratory findings included remarkable leukocytosis and eosinophilia, colonoscopy revealed erosion and ulceration in rectum and sigmoid, . After 2 days severe heart failure with pulmonary edema occurred with wrist drop, On the basis of the clinical features and histopathological findings, she was diagnosed with CSS and subsequently treatedConclusion: This case was rare presentation of churg- strauss with gastrointestinal involvement and fatal progressive manner, Improved awareness of gasterointestinal EGPA may allow for timely management of this disorder.