DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN OF ACINETOBACTER BAUMANII ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT (ICU)

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KHALEDI AZAD; BAHADOR ABBAS; MANSOORI NOOR MOHAMMAD; GHAZALI BINA MEHRAN; GHAZVINI KIARASH

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2015 | Volume:58 | Issue:7 Page(s): 376-380

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Title

DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN OF ACINETOBACTER BAUMANII ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT (ICU)

Author(s)

Keywords

ACINETOBACTER BAUMANNIIQ1

MDRQ2

ICUQ2

Abstract

Introduction: Nowadays ACINETOBACTER BAUMANNII strains resistant to multi-drugs (MDR) are as one of the most problematic opportunistic pathogens, especially in the intensive care unit (ICU) in the world. This study aimed to characterize the antibiotic susceptibility pattern of Acinetobacter baumanii isolated from patients in intensive care unit (ICU) of Motahari hospital, Gonbad, Golestan.Material and method: The clinical samples isolated from hospitalized patients in ICU sent to the laboratory for detecting ACINETOBACTER BAUMANNII by biochemical tests and confirmed by PCR and antibiotic susceptibility test performed and then the obtained data were analyzed by SPSS software and chi-square test.Results: According to the antibiotic susceptibility testing, from 50 ACINETOBACTER BAUMANNII isolates of ICU, 64%, 24% and 12% of isolates were MDR, Non MDR and XDR respectively. The highest rate of antibiotic resistance was to Ceftriaxone, Ticarcilline and Erythromycin, also the minimum resistance was to Minocycline.Conclusion: Due to the fact that the rate of MDR was high in this study, the antibiotic susceptibility test is necessary before prescribing antibiotics and the correct use of antibiotics should be considered. Since it was found in our study that all strains insensitive to Imipenem were susceptible to Tobramycin and Minocycline, for treatment of infections caused by strains which are resistant to Imipenem, the combination of other antibiotics such as Tobramycin can be used.

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APA: Copy

KHALEDI, AZAD, BAHADOR, ABBAS, MANSOORI, NOOR MOHAMMAD, GHAZALI BINA, MEHRAN, & GHAZVINI, KIARASH. (2015). DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN OF ACINETOBACTER BAUMANII ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT (ICU). MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 58(7), 376-380. SID. https://sid.ir/paper/52009/en

Vancouver: Copy

KHALEDI AZAD, BAHADOR ABBAS, MANSOORI NOOR MOHAMMAD, GHAZALI BINA MEHRAN, GHAZVINI KIARASH. DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN OF ACINETOBACTER BAUMANII ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT (ICU). MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2015;58(7):376-380. Available from: https://sid.ir/paper/52009/en

IEEE: Copy

AZAD KHALEDI, ABBAS BAHADOR, NOOR MOHAMMAD MANSOORI, MEHRAN GHAZALI BINA, and KIARASH GHAZVINI, “DETERMINATION OF ANTIMICROBIAL RESISTANCE PATTERN OF ACINETOBACTER BAUMANII ISOLATED FROM PATIENTS IN INTENSIVE CARE UNIT (ICU),” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 58, no. 7, pp. 376–380, 2015, [Online]. Available: https://sid.ir/paper/52009/en

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