Introduction: Due to the increasing development of science and technology in today’s world and updates in organizational factors, staff development becomes more essential. An educational program could be considered effective if it could appropriately change in participants’ knowledge and behavior. The aim of this study is to assess the training course of working with ECT (DC Shock device) for nurses based on the Kirkpatrick’s model.Methods: This evaluation study is based on the Kirkpatrick’s model, in which the efficacy of training course of working with ECT to nurses is assessed. A volunteer sample of 160 nurses participated in the project with informed consent. The training course was evaluated concerning four areas including reaction, learning, behavior, and outcome; then the overall efficacy rate of the course was calculated. Data was collected through researcher- made questionnaires whose validity and reliability were confirmed in a pilot study. Data was analyzed by Student t-test.Results: The mean scores of participants’ reaction (first level in Kirkpatrick model) to the content, instructor and facilities were 4.3±.35, 4.8±.41, and 4.1±.27, out of 5, respectively. The desirability rates (mean scores) for the four levels were: reaction (4.4±.45), learning (4.35±.24), behavior (3.85±.18), and the impact (4.33±.18). The mean of overall desirability rate of this course was 4.16±.41.Conclusion: The training course of working with ECT for nurses resulted in favorable outcomes in the three evaluated levels of reaction, learning and behavior, and was able to develop efficient changes in the impact level.