Most of the dairy industries in Iran discharge their wastewater to the municipal sewer system. Insufficient knowledge about the organic load coming from this industry has resulted in inadequate design and organic overloading in the municipal wastewater treatment plants of this category. The objective of this project was to estimate COD, BOD, and SS reduction of whey by using chemical coagulant and natural polymers. The experiments were accomplished in two stages: At first, dit1"erenl parameters of whey are measured. In this part COD, BOD5, TS and SS of whey were estimated to be 73000, 42000, 65000, and 1200mg/lit respectively, and BOD5/COD is considered to be approximately 0.6.1. In the second phase that was the main part of the experiments, the effect of different coagulants and natural polymers on the reduction of COD and SS of whey were tested. The results indicated that maximum removal efficiency of 20%-30% in total COD and more than 90% of SS were achieved depending on coagulant used. Hence chemical coagulation could be used as pretreatment of whey and for complete treatment, another methods may be used.