Yafteh
Year:2001 | Volume:3 | Issue:10|Papers Count:9

Rickets and softening of the bones (Osteomalacia) are disorders in which mineralizing of skeleton organic matrix is defect.This study was carried out to determine rickets prevalence rate in children under years old in Nurabad city.758 children were selected randomly as sample size and then clinical examinations ALK P test Ca, Ph, serum and wrist X-ray were done for each child.Results showed that the prevalence of pathologic level of ALK p. in the treatment population were 10.02% (morbid level), 84% (normal level) and 5.08% (reduced level) receptively (<90 IU/LI).Higher prevalence of rickets was associated with insufficient intake of vitamin D, number of children, LBW, history of similar disease in brother or sister and using anti- convulsant drugs. Prevalence of the disease was equal in both sexes and mean age of the patients was 2.4 years old.Among clinical signs, bow leg was the most common sign, accompanied radiologic findings in 95%of the patients, with elevated level of ALK Pin 61% of the cases.

Fortification is adding nutrients to a foodstuff. The nutrient may exist in that foodstuff natural1yor doesn't exist. SO, this process results in improvement of nutritional quality.The basic aim of food fortification with iron is to prevent iron deficiency in a population at longterm or middleterm .Vehicle and fortificant are two important factors in the fortification. Selection of suitable vehicle depends on vulnerable groups accessibility.Fortificant must have high bioavailability, cost benefit, and no effect on organoleptic specifications of the vehicle.Fortification is two types; public and target .Some countries have experienced iron fortification in national level. In Iran wheat is the best vehicle, because it is scanty food of a great number of Iran's people. But use of fortificant which can be suitable, is still debated.

HDL2 and HDL3 are the main subgroups of HDL-C .According to the researches.HDL2 is considered as an anti-risk factor in patients with cardiovascular diseases Measurement importance of these subgroups lead to devise different methods by researcher.In this study two methods of precipitation and electroforesis were compaired for measurement of the mentioned above subgroups. In precipitations method the subgroup of HDL-C were seperated in two stages using dextran sulfate (M.W=50000 dalt), MGCL2 and 6 H2O, and then the subgroups were determined through the enzumatic method and cholesterol content measurement by RA-I 000 apparatus.In electrophoresis method we used discontinuous gradient of polyacrylamid gel for analysis of HDL Subgroups.Data analysis gained from results showed no significant difference between two methods of measurement, so it can be said there is accordance between these two methods. Nevertheless two stages precipitation method by dextran sulfate, MgC12 and 6 H2O can be used as a simple, rapid and confident method in para clinical laboratories for measurement of HDL subgroups in patients with CHD.

Thyroid nodules are among common cases of patients referring to clinics and physicians offices. Regarding the possibility of malignancy of thyroid nodules there exist risk factors in causing the malignancy as well.This study was carried out to determine the malignancy of thyroid in pationts with thyroid nodules who had undergone surgery in shohadyee - Ashayer Hospital of khoramabad in 1998-2000.126 patients who, during four years, undergone thyroidectomy were studied. Needed data including age, sex family history, history of ray irradiation to the neek and head, and pathological report were taken from patients' records and after classification, analysis was done using descriptive statistics.Results showed that malignancy rate was 15.1%. The ratio of malignancy in females to males was 5.3 to 1 The kind of malignancy in 47.3% of them was papillary and in 36.8% follicular. Considering the role of ray irradiation to the neek and head and family history in thyroid malignancy but in this study no such case vas observed, therefore more studies is suggested about other risk factors causing thyroid malignancy e.g relation of Iodin deficiency and follicular carcinoma.

Nasocomial infections usually lead to receiving adeed drugs by patient, prolongation of hospitalization and even death of patient in some cases. In order to interrupt means of spread, identification of primary source, reservoirs, environment, prevalence and resistance of pathogen to antibiotic therapy is essential. In this research staphylococcus aureus, specially methicillin resistant staphylococcus aureus (MRSA) was studied as one of the most common microbes of nasocomial infections The study was conducted on 337 professional staff during three stages. Findings snowed that 10.4% of the staff were infected with S. aureus and 4.2% with MRSA. Nasal area was the most common site of contamination .ENT and eye wards were the most contaminated areas and the specialists were the most infected persons.The most antibiotic sensevity, among all isolated samples, was against chloramphenicol Methicilln and chloramphenicol sensevity in staphylococcus aureus was 54% and 83.8% respectively.

Vitiligo is a common depigmenting skin disease, associated with certain autoimmune diseases. Autoantibodies to several antigens including melanocytic antigens can be found in vitiligo Tyrosinase is a principle autoantigen of vitiligo .The present research, is a case - control study and was conducted on serum samples oblained from 99 patients with vitiligo and fom 99 – healthy subjects, age and sex matched with vitiligo patients to determine the antityrosinase autoantibodies titre using Dot immunobinding Assay(DIBA)The results are as follows:Among patients group 72 (72.7%) of them had generalized form of the disease and 27 (27.3%) of them had localized form of the disease. Antityrosinase autoantibodies were present in 96 (97%) of the patients and 70 (71%) of the controls. The mean of antityrosinase autoantibodies reverse titre in cases was higher than controls. This difference was statistically significant .The mean of antityrosinase autoantibodies reverse titre in generalized form of the disease was higher than localized form of it, but , the difference was not statistically significant. The mean of antityrosinase autoantibodies reverse titre in localized form of the disease was higher than the control group, but this difference was not statistically significant significant. Correlation between the antityrosinase autoantibodies titre, age and sex was not statistically significant. The mean difference of autoanibodies reverse titre between-under treatment and without treatment groups was not statistically significant. The results show that tyrosinase enzyine, can be the principle autoantigen of vitiligo.

Preeclampsia is a major cause of morbidity and mortality during pregnancy. Although the pathophysiology of preeciampsia has not yet been fully elucidated, several investigators have demonstrated through human and animal studies, the association of androgens, especially testosterone with hypertension.The purpose of the study was to determine maternal serum levels of androgens, especially testosterone, in patients with preeclampsia and its comparison with normotensive control subjects.Serum testosterone, dehydroepiandrosterone sulfate levels were measured in 30 subjects in the third trimester of pregnancy with documented preeclampsia and 30 healthy, normotensive women with similar maternal and gestational ages.All subjects were primigravid women with singleton pregnancies who referred to Asali Hospital.Total testosterone and free testosterone levels were significantly higher in patients with preeclampsia (206.2 ng/dl and 0.5 ng/dl) than in the control group (158.8 ng/dl and 0.2 ng/dl). There were no significant differences in dehydroepiandrosterone sulfate and maternal age, gestational age, body mass index and neonatal sex.Levels of the potent andreogen testosterone were significantly higher in primigravid women with preeclampsia than in normotensive women with similar gestational and maternal ages.This difference may indicate a role for testosteron in the pathogenesis of preeclampsia.

This cross sectional research was carried out to determine the prevalence of depression among the students of health faculty of kerman university of medical sciences in April 2001. The study was performed on all the students by census sampling and using Beck standardized questionnaire. Totally 346 students (80%of the students) completed the questionnaire. Acquired results showed that 61% out of all the subjects had different degrees of depression including 22% border depression, 15% slight depression, 17% average depression, 5% severe depression and 2% very severe depression. As well as there was no significant relation between the rate of depression and following variables: age, sex, marital status, residency, living resource, parents life, father level of education and term of study. In turn the rate of depression had a significant correlation with mothers job, field of study, final degree of study, university entrance year, field of study satisfaction, job future, physical and mental status of the student. In general the average rate of depression was higher in students with mental and physical disorders.

Epidermo dysplasiaverrucuformis is an inherited disorder in which body is susceptible to be effected with HPV viruses .In this disease multiple and widespred warts like planwarts and versicolour-like lesions demonstrate. Malignant changes are common too, but metastasis is rare. In this study cases were 2 sisters (second and fourth dildren of the family) with EV from two years ago. Both were treated using INF - a 3 mil (5 vials) in five trial weeks, and after 6, months no lesion recurred.