ANDROGEN LEVEL IN PATIENTS WITH PREECLAMPSIA

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YARI F.; GHAFARZADEH M.

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Journal: Yafteh Year:2001 | Volume:3 | Issue:10 Page(s): 39-41

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Information Journal Paper

Title

ANDROGEN LEVEL IN PATIENTS WITH PREECLAMPSIA

Author(s)

YARI F. | GHAFARZADEH M. | Issue Writer Certificate

Keywords

ANDROGENQ3

PREECLAMPSIAQ3

TESTOSTERONEQ2

Abstract

Preeclampsia is a major cause of morbidity and mortality during pregnancy. Although the pathophysiology of preeciampsia has not yet been fully elucidated, several investigators have demonstrated through human and animal studies, the association of ANDROGENs, especially TESTOSTERONE with hypertension.The purpose of the study was to determine maternal serum levels of ANDROGENs, especially TESTOSTERONE, in patients with PREECLAMPSIA and its comparison with normotensive control subjects.Serum TESTOSTERONE, dehydroepiandrosterone sulfate levels were measured in 30 subjects in the third trimester of pregnancy with documented PREECLAMPSIA and 30 healthy, normotensive women with similar maternal and gestational ages.All subjects were primigravid women with singleton pregnancies who referred to Asali Hospital.Total TESTOSTERONE and free TESTOSTERONE levels were significantly higher in patients with PREECLAMPSIA (206.2 ng/dl and 0.5 ng/dl) than in the control group (158.8 ng/dl and 0.2 ng/dl). There were no significant differences in dehydroepiandrosterone sulfate and maternal age, gestational age, body mass index and neonatal sex.Levels of the potent andreogen TESTOSTERONE were significantly higher in primigravid women with PREECLAMPSIA than in normotensive women with similar gestational and maternal ages.This difference may indicate a role for testosteron in the pathogenesis of PREECLAMPSIA.

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APA: Copy

YARI, F., & GHAFARZADEH, M.. (2001). ANDROGEN LEVEL IN PATIENTS WITH PREECLAMPSIA. YAFTEH, 3(10), 39-41. SID. https://sid.ir/paper/80181/en

Vancouver: Copy

YARI F., GHAFARZADEH M.. ANDROGEN LEVEL IN PATIENTS WITH PREECLAMPSIA. YAFTEH[Internet]. 2001;3(10):39-41. Available from: https://sid.ir/paper/80181/en

IEEE: Copy

F. YARI, and M. GHAFARZADEH, “ANDROGEN LEVEL IN PATIENTS WITH PREECLAMPSIA,” YAFTEH, vol. 3, no. 10, pp. 39–41, 2001, [Online]. Available: https://sid.ir/paper/80181/en

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