مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

40
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

16
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

Transarterial Chemoembolization Of Hepatocellular Carcinoma: Can Early Diffusion Weighted Imaging Predict Response?

Pages

  9-20

Abstract

 Purpose: We evaluated the role of early Diffusion Weighted Imaging (DWI) in predicting response to TACE in patients with HCC and compare the results with contrast enhanced Magnetic Resonance Imaging. Methods: 24 patients with documented HCC were taken up for TACE after a pre-procedural contrast CT and MRI. Post procedural DWI was taken on day 5-7 and the mean ADC values were documented and compared to pre procedural values. The change in ADC values was grouped into 4 categories: group 1-<25%, group 2 26-50%, group 3-51-75% and group 4->75%. The increase in ADC values signifying response was correlated with 5 week CEMRI scan (which has been the traditional gold standard for response evaluation) and a threshold ADC increase signifying response in majority of the cases was calculated. Results: The mean ADC of the lesions changed from 1. 21× 10-3 (pre TACE) to 2. 02× 10-3 mm2/sec (post TACE) [p<0. 001]. Taking CE MRI as gold standard, DWI imaging had a sensitivity of 80%, specificity of 94. 7% with a positive predictive value of 80%, negative predictive value of 94. 7% and overall accuracy of 91. 7%. Complete response was seen in19 (79%) and incomplete in 5 (21%) patients in our study. The change in ADC was significantly higher in responders (884. 15 ±,161. 60) as compared to non responders (564. 80 ±,221. 05) [p =0. 001]. Conclusion: Early DWI after TACE can predict response of a HCC lesion to chemoembolization. The change in ADC values can earmark responders from non-responders. Early DWI results are concordant with CEMRI results in most of the cases. DWI can act as a substitute to CEMRI when contrast administration is not advised.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    asma, Gulzar, tahleel, Shera, Ashraf Shah, Omair, Naseer, Choh, Tariq, Gojwari, mudaisr, Bhat, & shadab, Maqsood. (2021). Transarterial Chemoembolization Of Hepatocellular Carcinoma: Can Early Diffusion Weighted Imaging Predict Response?. BASIC & CLINICAL CANCER RESEARCH, 13(1), 9-20. SID. https://sid.ir/paper/1004446/en

    Vancouver: Copy

    asma Gulzar, tahleel Shera, Ashraf Shah Omair, Naseer Choh, Tariq Gojwari, mudaisr Bhat, shadab Maqsood. Transarterial Chemoembolization Of Hepatocellular Carcinoma: Can Early Diffusion Weighted Imaging Predict Response?. BASIC & CLINICAL CANCER RESEARCH[Internet]. 2021;13(1):9-20. Available from: https://sid.ir/paper/1004446/en

    IEEE: Copy

    Gulzar asma, Shera tahleel, Omair Ashraf Shah, Choh Naseer, Gojwari Tariq, Bhat mudaisr, and Maqsood shadab, “Transarterial Chemoembolization Of Hepatocellular Carcinoma: Can Early Diffusion Weighted Imaging Predict Response?,” BASIC & CLINICAL CANCER RESEARCH, vol. 13, no. 1, pp. 9–20, 2021, [Online]. Available: https://sid.ir/paper/1004446/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button