The first report of myocarditis followed by AstraZeneca vaccination in Iran

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SERVATYARI KARO; HASSANI AMIR

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Journal Paper

Paper Information

Journal: CHRONIC DISEASES JOURNAL Year:2022 | Volume:10 | Issue:2 Page(s): 1-4

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Title

The first report of myocarditis followed by AstraZeneca vaccination in Iran

Author(s)

SERVATYARI KARO | HASSANI AMIR | Issue Writer Certificate

Keywords

AstraZeneca

Vaccination

Myocarditis

COVID-19

Iran

Abstract

BACKGROUND: Coronavirus disease 2019 (COVID-19) is an emerging disease caused by the coronavirus. The initiation of vaccination significantly reduced the incidence and mortality of these patients. Some studies reported myocarditis as a rare complication after messenger ribonucleic acid (mRNA)-based vaccines (such as Pfizer). CASE REPORT: The patient was a 26-year-old man without any history of the underlying disease with typical chest pain which spread to the back and left arm,he was diagnosed with myocarditis after the second dose of the AstraZeneca vaccine. The mechanism of myocarditis after AstraZeneca is not known precisely. It seems to be due to the AstraZeneca vaccine using adenovirus as a vector of the spike (S) protein of the virus, and it causes the production of antibodies in the body, while adenovirus can be one of the causes of myocarditis. On the other hand, it may be due to spike protein-mediated toxicity, which causes an inflammatory reaction such as myocarditis after the virus protein enters the bloodstream and eventually accumulates in various tissues, including the heart. CONCLUSION: Myocarditis is a rare complication of the AstraZeneca vaccine, and this study could not recommend neglecting this vaccine.

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APA: Copy

SERVATYARI, KARO, & HASSANI, AMIR. (2022). The first report of myocarditis followed by AstraZeneca vaccination in Iran. CHRONIC DISEASES JOURNAL, 10(2), 1-4. SID. https://sid.ir/paper/1004899/en

Vancouver: Copy

SERVATYARI KARO, HASSANI AMIR. The first report of myocarditis followed by AstraZeneca vaccination in Iran. CHRONIC DISEASES JOURNAL[Internet]. 2022;10(2):1-4. Available from: https://sid.ir/paper/1004899/en

IEEE: Copy

KARO SERVATYARI, and AMIR HASSANI, “The first report of myocarditis followed by AstraZeneca vaccination in Iran,” CHRONIC DISEASES JOURNAL, vol. 10, no. 2, pp. 1–4, 2022, [Online]. Available: https://sid.ir/paper/1004899/en

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