The Prevalence of Hepatitis C Virus (HCV) Infection and Genotypes in Patients with Hemophilia and Other Blood Coagulopathies in Mashhad, Iran

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BADIEI ZAHRA; AHMADI GHEZELDASHT SANAZ; SIMA HAMID REZA; Habibi Meysam; Khamoushi Mohsen; Azimi Ahmad; HEDAYATI MOGHADDAM MOHAMMAD REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Archives of Medical Laboratory Sciences Year:2021 | Volume:7 | Issue:1 Page(s): 0-0

Download Full-Text

View:

Download:

Cites:

Information Journal Paper

Title

The Prevalence of Hepatitis C Virus (HCV) Infection and Genotypes in Patients with Hemophilia and Other Blood Coagulopathies in Mashhad, Iran

Author(s)

Keywords

Blood Coagulation Disorders

Genotype

HCV Infection

Iran

Prevalence

Abstract

Background and Aim: Patients with blood coagulopathies treated with multiple transfusions have a high risk to acquire some viral infections such as hepatitis C. This research was aimed to identify hepatitis C virus (HCV) infection Prevalence, and the viral Genotypes among patients with hemophilia and other inherited coagulopathies in Mashhad, Iran. Methods: Medical records of 760 patients with inherited coagulopathies including hemophilia were reviewed in Sarvar Clinic of Mashhad. Plasma samples were subjected to detect antibodies against HCV (anti-HCV) by enzymelinked immunosorbent assay. HCV RNA and Genotypes were determined by a real-time polymerase chain reaction (PCR) method. Results: Totally 128 individuals (16. 8%) including patients with hemophilia (n=116) and individuals with other coagulopathies (n=12) were found to be seropositive for anti-HCV. They comprised 122 men and six women with a mean age of 31. 6 ±,10. 5 years. The PCR results were available for 118 patients, of whom 86 individuals (72. 9%) were found to have detectable HCV RNA in their serum. The most frequent Genotypes were 1a and 3a (49. 1% and 35. 8%, respectively). HCV Genotypes were not significantly correlated with the patients’,age (p=0. 477) as well as with the serum levels of alanine aminotransferase (p=0. 655) and aspartate aminotransferase (p=0. 332). Conclusion: The patients with Blood Coagulation Disorders had a greater Prevalence of HCV Infection in comparison with the general population in our region. The most common subGenotypes of HCV were 1a, and 3a, respectively. These results could assist professionals to choose more efficient approaches for the management of their patients.

Cites

No record.

References

No record.

Cite

APA: Copy

BADIEI, ZAHRA, AHMADI GHEZELDASHT, SANAZ, SIMA, HAMID REZA, Habibi, Meysam, Khamoushi, Mohsen, Azimi, Ahmad, & HEDAYATI MOGHADDAM, MOHAMMAD REZA. (2021). The Prevalence of Hepatitis C Virus (HCV) Infection and Genotypes in Patients with Hemophilia and Other Blood Coagulopathies in Mashhad, Iran. ARCHIVES OF MEDICAL LABORATORY SCIENCES, 7(1), 0-0. SID. https://sid.ir/paper/1019740/en

Vancouver: Copy

BADIEI ZAHRA, AHMADI GHEZELDASHT SANAZ, SIMA HAMID REZA, Habibi Meysam, Khamoushi Mohsen, Azimi Ahmad, HEDAYATI MOGHADDAM MOHAMMAD REZA. The Prevalence of Hepatitis C Virus (HCV) Infection and Genotypes in Patients with Hemophilia and Other Blood Coagulopathies in Mashhad, Iran. ARCHIVES OF MEDICAL LABORATORY SCIENCES[Internet]. 2021;7(1):0-0. Available from: https://sid.ir/paper/1019740/en

IEEE: Copy

ZAHRA BADIEI, SANAZ AHMADI GHEZELDASHT, HAMID REZA SIMA, Meysam Habibi, Mohsen Khamoushi, Ahmad Azimi, and MOHAMMAD REZA HEDAYATI MOGHADDAM, “The Prevalence of Hepatitis C Virus (HCV) Infection and Genotypes in Patients with Hemophilia and Other Blood Coagulopathies in Mashhad, Iran,” ARCHIVES OF MEDICAL LABORATORY SCIENCES, vol. 7, no. 1, pp. 0–0, 2021, [Online]. Available: https://sid.ir/paper/1019740/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops